Head: Arnaud Ferry
Our group is focused on muscle physiology in normal, muscular exercised, aged and pathologic conditions:
. Impact of neuromuscular disease on muscle function and motor performance (i.e., characterization of rodent models)
. Evaluation of therapies on muscle function. Preclinical studies in rodent models of neuromuscular diseases with the collaboration of the muscle evaluation PTF at UMS28 (S. Morosan and M. Lemaitre)
. Integrative physiology of healthy skeletal muscle
. Beneficial effects of different types of chronic exercise in neuromuscular diseases mouse models
Group members
Arnaud FERRY, PhD, PU, Group leader
Dylan MOUTACHI, IE
Alexandra MONCEAU, Doctorate
Contact : arnaud.ferry@upmc.fr
Last publications
- Valproic acid reduces muscle susceptibility to contraction-induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy. Moutachi D, Lemaitre M, Delacroix C, Agbulut O, Furling D, Ferry A. Clin Exp Pharmacol Physiol. 2023 Sep;50(9):749-756. doi: 10.1111/1440-1681.13804. Epub 2023 Jun 29. PMID: 37381823
- Arandel L, Matloka M, Klein AF, Rau F, Sureau A, Ney M, Cordier A, Kondili M, Polay-Espinoza M, Naouar N, Ferry A, Lemaitre M, Begard S, Colin M, Lamarre C, Tran H, Buée L, Marie J, Sergeant N, Furling D. Reversal of RNA toxicity in myotonic dystrophy via a decoy RNA-binding protein with high affinity for expanded CUG repeats.Nat Biomed Eng. 2022 Feb 10. doi: 10.1038/s41551-021-00838-2. Epub ahead of print. PMID: 35145256.
- Monceau A, Moutachi D, Lemaitre M, Garcia L, Trollet C, Furling D, Klein A, Ferry A. Dystrophin restoration after AAV-U7-mediated dmd exon-skipping is modulated by muscular exercise in the severe D2-mdx DMD murine model. The Amercan Journal of Pathology 2022 Sep 13:S0002-9440(22)00279-6 ; doi: 10.1016/j.ajpath.2022.07.016.
- Monceau A, Delacroix C, Lemaitre M, Revet G, Furling D, Agbulut O, Klein A, Ferry A. The beneficial effect of chronic muscular exercise on muscle fragility is increased by Prox1 gene transfer in dystrophic mdx muscle. PLoS One, 2022. 17(4):e0254274; doi: 10.1371/journal.pone.0254274.
Other publications :
http://www.ncbi.nlm.nih.gov/pubmed/?term=Ferry+A+and+Université