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1381 news items
Research
The diagnostic and pathophysiological challenges of toxic vacuolar myopathies
On 09/10/2026
Clinician and researchers from the Institute of Myology, in collaboration with international researchers, have investigated myopathies induced by chloroquine (and its derivatives, referred to by…
Research
Muscle biopsy: a diagnostic technique that remains useful despite advances in genetics
On 08/10/2026
Italian researchers have examined the diagnostic value of muscle biopsy at a time when high-throughput sequencing (NGS) and immunoassays are increasingly relegating it to a…
Research
Stabilisation of motor function two years after switching to alfa-sialidase in Pompe disease
On 08/10/2026
A French study analysed real-world data from 47 adults with late-onset Pompe disease who switched to alfa-glucosidase (Nexviadyme) after treatment failure with alfa-glucosidase (Myozyme). Longer-term…
Research
Modulation of the muscle satellite cell pool (MuSC) by GDF5: a potential therapeutic benefit for DMD
On 08/10/2026
Researchers from the Center of Research in Myology* at the Institute have demonstrated the benefits of treatment with growth and differentiation factor 5 (GDF5) in…
Research
Plasma proteomics studies to assess the clinical manifestations and tissue damage associated with certain inflammatory myopathies
On 06/10/2026
An international consortium of researchers, including a French team, analysed the proteomic profiles of 201 patients seen in Stockholm who were suffering from inflammatory myopathy:…
Research
Autoimmune conditions that test positive for anti-Ku antibodies carry a significant risk of pulmonary complications
On 05/10/2026
Clinicians from ten centres within the Assistance-Publique Hôpitaux de Paris (APHP) compiled and compared the clinical and laboratory data of 154 adults with positive anti-Ku…
Research
At what levels are CPK levels actually considered pathological?
On 05/10/2026
British and Canadian researchers have sought to establish non-pathogenicity reference ranges for creatine phosphokinase (CPK) levels measured in routine clinical practice: According to the authors,…
Research
Gefurulimab successfully completes Phase III trials in myasthenia gravis with anti-RACh+ antibodies
On 01/10/2026
The Phase III PREVAIL trial evaluated gefurulimab (or ALXN1720) against a placebo in 20 countries, including France, in 249 adults with a generalised form of…
Research
Initial results from the Phase III trial of del-desiran in Steinert disease
On 29/09/2026
In September 2026, Novartis announced the initial results of the Phase III HARBOR trial evaluating delpacibart andedesiran (del-desiran or AOC 1001) in type 1 myotonic…
Patient care
Diabetes is more common in late-onset dermatomyositis, regardless of corticosteroid use
On 24/09/2026
A retrospective analysis was carried out using the medical records of 434 patients with late-onset dermatomyositis, matched with a control cohort. These results confirm the…
Research
An antisense strategy to specifically target one of the mutations responsible for FOP
On 23/09/2026
Canadian researchers have developed antisense oligonucleotides (DNA/RNA gapmers) designed to selectively target the R206H mutation in the ACVR1 gene – which is most commonly responsible…
Research
Diaphragmatic ultrasound: a promising biomarker for the risk of respiratory complications in Steinert myotonic dystrophy
On 15/09/2026
French clinicians investigated diaphragmatic function in patients with Steinert’s myotonic dystrophy (DM1) using an ultrasound method, which is by definition non-invasive: The authors highlight the…
Events
MYOLOGY 2027: registration and abstract submission are now open
On 14/09/2026
The 9th International Congress of Myology, MYOLOGY 2027, will take place in Strasbourg from 10 to 13 May 2027. Throughout the four days, leading international…
Research
Clinical presentations that can sometimes be misleading in women who are carriers of FHL1-related myopathy
On 07/09/2026
French clinicians have compiled the clinical and genetic data of five female patients who were ultimately diagnosed as ‘carriers’ of myopathy linked to the FHL1…
Research
The importance of collagen VI in muscle fibrosis and impaired regeneration
On 03/09/2026
The ‘Cellular and Molecular Orchestration in Muscle Regeneration during Ageing and in Disease’ team, led by Capucine Trollet at the Institute’s Center for Research in…
Research
A better understanding of the barriers and enablers of physical activity in myasthenia gravis
On 19/08/2026
Led by Simone Birnbaum, a researcher at the Neuromuscular physiology and neuromuscular Evaluation Lab, in collaboration with the AFM-Telethon, the national MYaEX study involved 455…
Patient care
A combination therapy involving an antisense oligonucleotide and an HDAC6 inhibitor appears promising for SMA
On 21/07/2026
Researchers in Lyon have investigated, both in vitro and in vivo, the potential therapeutic synergy between the type 6 HDAC inhibitor (givinostat), which is already…
Patient care
The benefits of the ketogenic diet in the treatment of myasthenia gravis
On 10/07/2026
German clinicians have investigated the benefits of the ketogenic diet (very high in fat and low in carbohydrates) in autoimmune myasthenia gravis, following on from…
Research
In myasthenia gravis, complement inhibitors increase life expectancy… and cardiovascular risk!
On 08/07/2026
Two German researchers investigated the benefits and potential complications – particularly cardiovascular ones – of a new class of drugs used to treat refractory forms…
Research
A review of myositis in the NEJM, authored by two French experts
On 24/06/2026
In line with their research over several decades and the advances they have already spearheaded, Professors Olivier Benveniste and Yves Allenbach (the Inflammatory Myopathies &…