French experience of spinal surgery in patients with type II SMA

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Researchers at the Centre de Référence des maladies neuromusculaires at Trousseau Hospital in Paris have studied data from patients with SMN1 type II-related proximal spinal muscular atrophy operated on for spinal deformity:

  • the study included 25 patients operated on between 2009 and 2022 and divided into two groups,
  • receiving either magnetic growth rods (MCGR type) (17/25) or posterior spinal arthrodesis (AVP) (9/25),
  • surgery was performed on average slightly earlier in the MCGR group (9.7 years versus 12.6 years),
  • correction of spinal deformity was slightly better with arthrodesis (55% vs. 44%),
  • surgery was well tolerated (no need for blood transfusions, and identical impact on vital capacity pre- and post-operatively).

The authors emphasise the value of fixation in combating pelvic obliquity.

 

Growth-friendly Technique or Posterior Spinal Fusion With T-construct Pelvic Fixation in Nonambulatory Spinal Muscular Atrophy With Severe Scoliosis. Gaume M, Denamur S, Aubertin G et al. J Pediatr Orthop. 2025 May

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