Efgartigimod is more rapidly effective than intravenous immunoglobulins in myasthenia gravis

Chinese clinicians compared two immunotherapies for generalised forms of autoimmune myasthenia gravis:

  • 51 patients with moderate to severe myasthenia gravis requiring immunotherapy took part in the study,
  • 26 received a single course of intravenous efgartigimod, whilst the other 25 received intravenous immunoglobulins,
  • after one month of treatment, the efgartigimod group reached a minimal level of symptoms more quickly than the immunoglobulin group,
  • this benefit was also greater in terms of daily activity scores (MGADL),
  • however, this advantage diminished over time, after three and six months of treatment.

To achieve a faster therapeutic response, the authors recommend the use of efgartigimod.