An Italian study on anaesthetic practice in Charcot-Marie-Tooth disease

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The Italian consortium dedicated to Charcot-Marie-Tooth disease (CMT) has carried out a survey on the procedures, patient experiences and outcomes of anaesthesia administered to patients with CMT:

  • a specially designed self-administered questionnaire was distributed to patients listed in the CMT-Italy register as well as to control subjects,
  • which examined all types of anaesthesia, whether general (with or without intubation), axial (epidural and others) or regional (various blocks),
  • 290 patients with CMT and 94 healthy control subjects completed the questionnaire, corresponding to 508 and 161 anaesthetic procedures respectively,
  • they reported very few post-anaesthetic complications in both groups, which were mostly transient.

The authors highlight this good tolerance, although further, more detailed studies, better supported by objective measurements, are needed to confirm this.

Patient-Reported Complications and Outcomes of General, Central Neuraxial, and Peripheral Regional Anesthesia in Charcot-Marie-Tooth. Bertini A, Gemma M, Manganelli F et al. Disease. Neurol Genet. 2026 Aug

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