Cardiac involvement is possible in autoimmune necrotizing myopathies

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Chinese researchers studied all their cases of autoimmune necrotizing myopathy (AINM) over the period 2011-2022 with a focus on possible cardiac complications:

  • Fifty-seven patients with AINM were included in the study,
  • 56% had anti-SRP autoantibodies, 21% had anti-HMGCR autoantibodies and 23% were seronegative,
  • almost half had abnormalities on cardiological check-up including cardiac rhythm and/or ventricular function disorders.

These data confirm the results of previous studies and should encourage clinicians to carry out a full cardiological check-up in the event of a diagnosis of AINM.

 

Characteristics of cardiac involvement in immune-mediated necrotizing myopathy. Liu M, Lin Y, Qiao L, Front Immunol. 2023 Feb 28;14:1094611

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