Experts from the institute will present their research findings at Myology 2024

Researchers and clinicians from the Institute of Myology will be presenting their findings at the next international myology congress, Myology 2024, organized by AFM-Téléthon from April 22 to 25.

Over 70 international speakers will take the floor in 23 plenary and parallel sessions and 7 industry symposia, and more than 400 scientific posters will be discussed over the four days.

Our scientific and clinical experts will be delighted to welcome you to our stand no. 3, in the Havana hall, for discussions throughout the congress.


8 selected oral communications to be presented to the international community by our researchers:

  • Tuesday 23 April

• 11:30 – Capucine Trollet – Cellular actors and ECM components of human fibrosis in myopathies

• 11:30 – Ana Ferreiro – ASC-1 related myopathy reveals transcriptional co-activation as a new regulator of myogenesis: expanding the molecular spectrum and identifying the mechanisms of an emerging congenital myopathy

• 14:30 – Fiorella Grandi – RNA-sequencing of Type II SMA paravertebral muscle after treatment reveals distinct molecular subtypes

  • Wednesday 24 April

• 10:30 > 12:00 – Tanya STojkovic – Charcot-Marie-Tooth disease: an overview of genetic and phenotypic variability

• 16:00 – Jean-Yves Hogrel – Natural history studies : challenges and limitations
• 17:15 – Harmen Reyngoudt – Longitudinal quantitative MRI of forearm and arm muscles in dysferlinopathy

  • Thursday 25 April

• 10:30 – Olivier Benveniste – Myositis classification for targeted treatments

• 15:30 – Rozen Le Panse – Origin of the thymic interferon type I signature in myasthenia Gravis: role of endogenous nucleic acids


3 sessions chaired by institute experts:

  • Tuesday 23 April

08:30 > 10:00 – Fabrice Chrétien

10:30 > 12:00 – Gillian Butler-Browne

  • Wednesday 24 April

14:30 > 16:00 – France Pietri-Rouxel


Poster flash session

  • Wednesday 24 April

16:00 – oral presentation of Christel Gentil‘s poster – GDF5 over expression improves physiopathologie of DMD in mdx mouse muscle


3 presentations at industry symposia:

  • Tuesday 23 April

SYMPO2 • INDUSTRY SYMPOSIUM // LUPIN – Myotonia: should we reach a consensus on patient needs?
• 13:30 – Guillaume Bassez – Debate – expert opinions on myotonia in myotonic dystrophies (DM) and non-dystrophic myotonia (NDM)

  • Wednesday 24 April

SYMPO6 • INDUSTRY SYMPOSIUM // ALEXION – Legacy and Innovation: The Potential of Complement in Myasthenia Gravis
• 17:30 – Anthony Béhin – Burden of Disease and Role of Complement in MG
• 18:30 – Anthony Béhin – MG Treatment guidelines in the context of Clinical Practice in France


At the same time, 46 scientific posters will be presented and explained by researchers from the Institute of Myology during breakout sessions throughout the congress, in the Havana hall:

Valérie Allamand – Refined pro-fibrotic cellular models for detailed extracellular matrix analysis in collagen VI-related dystrophies

Manon Beaujean – Myopilot, a project to compare the regenerative efficacy of several categories of myogenic progenitors in vivo

Louise Benarroch – Cellular and genomic features of myo-converted fibroblasts, an alternative cellular model to myoblasts

Marion Benoist – Machanosensitive clathrin and  dynamin 2 platforms regulate YAP/TAZ signaling in skeletal muscle and rare defective in centronuclear myopathy

Anne Bertrand – In vivo gene therapy for striated muscle laminopathy

Rabah Ben Yaou – DYS: the French registry dedicated to Dystrophinopathies

Anne Bigot – Human myoblasts and FAPs cell lines: easy-to-use models to study neuromuscular diseases

Simone Birnbaum – Exercise training for autoimmune myasthenia gravis (MG): A review of safety and effectiveness based on existing literature

Simone Birnbaum – A French version of the modified Spinal Muscular Atrophy Functional Rating Scale (SMAFRS)

Simone Birnbaum – Perceived barriers & facilitators to exercise in autoimmune myasthenia gravis (MG): The MYaEX study

Dounia Bouragba – Human muscle cells secretome in Dysferlinopathy

Aly Bourguiba – Unraveling the role of GDF5 therapeutic potential in Amyotrophic Lateral Sclerosis

Ericky Caldas de Almeida Araujo – Changes in water compartmentation in the skeletal muscle of Golden Retriever Muscular Dystrophy (GRMD) dogs revealed by T2 relaxometry and intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI)

Linda Chenane – Deciphering the link between interferon stimulated genes and regeneration using spatial transcriptomics in dermatomyositis

Catherine Coirault – A-type lamins are crucial to preserve chromatin states during mechanical loading in skeletal muscle

Valérie Decostre – Quantification of skeletal muscle weakness in adult patients with laminopathies

Céline Douarre – Role of the microtubule-associated protein Stathmin 2 in the post-synaptic differentiation of the neuromuscular junction

Nadine Dragin – IL-23/Il-17 involvement in thymic and neuromuscular defects in autoimmune myasthenia gravis

Sestina Falcone – CaVβ1A and CaVβ1E embryonic isoforms in adult skeletal muscle, a Mbnl1 related-expression

Romain Feigean – Key determinants of impaired gait in adults with neuromuscular disease : a multiparametric and multimodal analysis

Anne Forand – Long-term dystrophin replacement therapy causes cardiac inflammation in a severely affected mouse model for Duchenne Muscular Dystrophy

Yves Fromes – MR-based characterization of muscle aging in a cohort of healthy volunteers

Maxime Gelin – Exploring the role of GDF5 in neuromuscular system during growth and physical activity

Stéphanie Godard-Bauché – Role of lamin A/C in the maintenance of AChR at the neuromuscular junction in Emery-Dreifuss muscular dystrophy.

Grégoire Haouy – Deciphering the role of R-loops in CTG repeat instability involved in DM1

Edouard Hemery – Characterization of human thymic macrophages in Myasthenia Gravis

Abdessamad Kachal – Predictive Model to Identify Higher Risk of Non-Invasive Ventilation in DM1 Patients

Marie Kervella – Three-dimensional Genome Architecture in Cardiac Muscle Cells: Pathophysiological Implications in Dilated Cardiomyopathy Caused by LMNA gene mutations

Marine Leconte – DNA damage repair in LMNA-related congenital muscular dystrophy

Béatrice Matot – Development of a pipeline to compare magnetic resonance imaging with histological analysis of mouse skeletal muscles

Célia Martin – MBNL deficiency in spinal motor neurons compromises neuromuscular junction maintenance and gait coordination: implication for Myotonic Dystrophy

Benjamin Marty – Quantitative magnetic resonance imaging for predicting disease progression in thigh muscles of Duchenne muscular dystrophy patients

Béatrice Matot – Development of a pipeline to compare magnetic resonance imaging with histological analysis of mouse skeletal muscles

Sabrina Mazzucchi – Investigating the role of SMN1 in R-loop formation during Spinal Muscular Atrophy (SMA) pathogenesis

Pauline Megalli – Implication of mutant DMPK RNA expressed in motor neurons in Myotonic Dystrophy type 1

Hadidja Rose Mouigni – Study of potential regulators of PABPN1 in skeletal muscle

Laura Muraine – Cellular actors and ECM components of human fibrosis in myopathies

Isabelle Nelson – Clinical, morphological and proteomic features of patients suspected of X-linked myopathy with excessive autophagy (XMEA)

Sofia Sosa-Marmol – Improving the immunomodulatory capacities of mesenchymal stem cells and their extracellular vesicles in view of treating Myasthenia gravis

Alain Sureau – Development of an inducible mouse model for Myotonic Dystrophy

Stéphanie Tomé – Single-Molecule long read sequencing in Myotonic Dystrophy type 1

Massire Traore – GDF5 as rejuvenating treatment for age-related neuromuscular failure

Delphine Trochet – Development of versatile allele-specific siRNAs able to silence all DNM2 mutations

Frédérique Truffault – Juvenile Myasthenia Gravis in a French cohort: Focus on thymic histology

Stéphane Vasseur – Biological ressources center for research

Laura Virtanen – Single-cell Spatio-Temporal profiling of striated muscle cell populations in Duchenne Muscular Dystrophy