Interview with
RSS feedFiorella Grandi, winner of the prestigious Marie Sklodowska-Curie 2022 postdoctoral fellowship – Interview with F. Grandi and P. Smeriglio
Fiorella Grandi started a postdoctoral fellowship in October 2022 in the Epigenetics and biotherapies for motor neuron disorders (ALS & SMA) group led by Piera Smeriglio. She is a laureate of the MSCA Postdoctoral Fellowships 2022 call (Marie Skłodowska-Curie Actions – Horizon Europe). Her project* focuses on the epigenetic mechanisms** that influence the efficacy of … [Read more]
« Muscle is a real public health issue and should be recognised as such » – Interview with Laurence Tiennot-Herment
Interview with Laurence Tiennot-Herment, President of AFM-Telethon and Institute of Myology Association. Why is muscle a public health issue? As patients with neuromuscular diseases know all too well, muscles play a vital role in motor, respiratory and cardiac functions. But they are also affected in many other diseases such as cancer or diabetes. In other words, … [Read more]
Cytoskeletal involvement in dilated cardiomyopathy caused by LMNA gene mutations – Interview with Caroline Le Dour
Caroline Le Dour is a post-doctoral fellow in the Signaling Pathways & Striated Muscles team led by Antoine Muchir, at the Institute’s Myology Centre for Research. She is first author of a paper published in Nature Communications which focuses on the interaction of actin and microtubule cytoskeletons in cardiomyopathy caused by LMNA gene mutations. What … [Read more]
Characterisation of PABPN1 aggregates in OPMD – Interview with Capucine Trollet
The results of an international study conducted by the Institute’s Capucine Trollet and Vincent Mouly team have just been published in Acta Neuropathologica. The article relates to the characterisation of PABPN1 aggregates performed on a unique series of 90 muscle biopsies from OPMD patients, collected from clinicians in France, Canada, the Netherlands and Israel, and on … [Read more]
A tool to evaluate cardiac risk in patients with mitochondrial disease – Interview with Karim Wahbi
Prof. Karim Wahbi, a cardiologist, has just published the results of an international study that he coordinated with his “Registries and databases” team at the Institute. The article relates to the prediction of cardiac consequences (complications) in adult patients with mitochondrial diseases*. What is the background to your conduct of this work? We have been … [Read more]
DM1: RNA toxicity alters astrocyte morphology, adhesion and migration
Mario Gomes-Pereira and his team* have just published a paper in Nature Communications** on the toxicity of mutant RNA that alters the morphology, adhesion and migration of astrocytes in mice and humans with myotonic dystrophy type 1 (DM1). Interview with Mario Gomes-Pereira. What is the background to this work? DM1 is a neuromuscular disease … [Read more]
Report of the 2022 AcadeMYO session
Andoni Urtizberea reports on the 2022 session of AcadeMYO, the fully virtual version of the Institute’s Myology Summer School, which was held from 11 to 13 July. What was the profile of the students who participated this year? We had 44 registered participants from 27 countries: Chile, Argentina, Brazil, Colombia, Russia, Latvia, USA, Canada, Australia, … [Read more]
Identification of a new communication pathway in the neuromuscular junction
A study conducted by the “Neuromuscular connectivity in health and pathologies” team led by Laure Strochlic and Bertrand Fontaine at the Institute’s Myology Centre for Research has just been published in Science Signaling*. This work demonstrates the existence of a new communication pathway in the neuromuscular junction that is active both during embryogenesis and at … [Read more]
Endothelin: a new player in muscle fibrosis
Mona Bensalah completed her thesis under the supervision of Elisa Negroni and Vincent Mouly in the team “Cellular and molecular orchestration in muscle regeneration, during aging and in pathologies” directed by Capucine Trollet and Vincent Mouly, at the Institute’s Myology Research Centre. Her work, completed by that of Laura Muraine, has just been published in … [Read more]
My thesis in 180 seconds: Louison Lallemant, 2022 Public prize winner
Louison Lallemant is a doctoral student in the group of Mario Gomes-Pereira and Geneviève Gourdon within the REDs team led by Denis Furling and Geneviève Gourdon, at the Institute’s Myology Centre for Research. She has just won the Public Prize awarded by Internet users and the public attending the Sorbonne University Final of the “My … [Read more]
