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Engineering muscle for human transplant – Interview with Bruno Cadot

In August 2023, Bruno Cadot won a call for proposals organised by the German National Innovation Fund (SPRIN-D) to finance his innovative project to create a synthetic muscle, combining chemistry and biology. Now that proof of concept has been achieved in mice, the next step is to make the transition to human transplants. Interview with Bruno … [Read more]

The Institute of Myology, partner in the European Dreams project – Interview with Stéphane Vassilopoulos

Dreams (Drug REpurposing and Artificial intelligence for Muscular disorderS) is an innovative project funded under a European call for tenders for 5 years, with the aim of developing an innovative methodology combining AI, stem cells and pharmacological screening to identify treatments for 5 muscular disorders. It is coordinated by Dr Xavier Nissan, Director of Research … [Read more]

The expertise of the NMR laboratory used to monitor the growth of a patient’s heart

Benjamin Marty is co-leader of the NMR and Spectroscopy Laboratory at the Institute’s  Neuromuscular Investigation Center. Together with Yves Fromes, also a researcher in this NMR lab, they just published an article* in The Lancet, in collaboration with Prof Kamenicky, describing the longitudinal muscular (skeletal and cardiac) exploration of a patient with hypopituitary dwarfism treated … [Read more]

Mariko Okubo awarded at the WMS for the discovery of a potential new role for lamins

Mariko Okubo is a post-doctoral researcher in the Myology Centre for Research in the « Myomatrix & Myonucleus Related Diseases: Genetics & Pathophysiology » team. She is a Japanese Pediatric Neurologist and came to Paris two years ago. She was awarded the Léa Rose Prize at the WMS annual conference held from 3 to 7 … [Read more]

Louise Benarroch wins Elsevier Runner Up Award at WMS 2023

Louise Benarroch is a post-doctoral researcher in the “Myomatrix & Myonucleus Related Diseases: Genetics & Pathophysiology” team led by Gisèle Bonne in the Institute’s CRM. Her latest work on the characterisation of a cellular model for muscle diseases was published* at the end of August, and was also presented at the 28th International Congress of … [Read more]

Identification of a new form of congenital myasthenic syndrome – Interview with M. Masingue and S. Bauché

The case of a patient presenting an atypical form of congenital myasthenic syndrome with the identification of a new mutation in the LRP4 gene has just been published in the journal Science Reports*. Result of a close collaboration between French scientists including clinicians from the Service of Neuro-Myology and researchers from the Myology Centre for … [Read more]

Bruno Cadot wins the Tremplin ASEAN prize awarded by the French Ministry of Higher Education and Research and the French Academy of Sciences

Bruno Cadot, a researcher in the “Physiopathology & therapy of autosomal dominant centronuclear myopathy” team led by Marc Bitoun at the Myology Research Centre, has just been awarded the Tremplin ASEAN prize by the French Ministry of Higher Education and Research and the French Academy of Sciences. This prize rewards existing cooperation between two teams, … [Read more]

Introduction to research in myology at the Institute for SU medical students – Interview with Guillaume Bassez

The Institute welcomed its first class of medical students for an introduction to research in the field of myology in April 2023. This week of training, which is part of the medical curriculum at Sorbonne University, was organised by Guillaume Bassez, neurologist and head of a research group in the Repeat Expansions & Myotonic Dystrophy … [Read more]

Role of caveolae in T-tubule formation in the muscle cell – Interview with Eline Lemerle and Stéphane Vassilopoulos

Eline Lemerle completed her thesis* under the supervision of Stéphane Vassilopoulos, in Marc Bitoun’s team (Muscle Organization & Therapy of Dominant Centronuclear Myopathy) at the Institute’s Myology Centre for Research. Her work on the formation of T-tubules in the muscle cell and more specifically on the role of caveolae, has just been published in the … [Read more]

Cross-sectional study of neuromuscular fatigue in autoimmune myasthenia – Interview with Simone Birnbaum

Simone Birnbaum, a researcher at the Neuromuscular Physiology and Evaluation Laboratory directed by Jean-Yves Hogrel (NIC, Institute of Myology) has just published an article assessing neuromuscular fatigue in persons with Myasthenia gravis in the journal Clinical Neurophysiology. Interview with Simone Birnbaum. What was the aim of the study? Myasthenia gravis (MG) is a rare disease characterized by … [Read more]