De nombreux chercheurs et cliniciens de l’Institut de Myologie présenteront leurs travaux de recherche et leurs résultats au prochain congrès international de myologie organisé par l’AFM-Téléthon du 22 au 25 avril, Myology 2024.
Plus de 70 conférenciers internationaux prendront la parole au cours de 23 sessions plénières et parallèles et 7 symposia organisés par des industriels, et plus de 400 posters scientifiques seront commentés au cours de ces quatre jours.
Nos experts scientifiques et cliniques se feront un plaisir de vous accueillir sur notre stand n°3, dans le hall Havane, pour partager des discussions tout au long du congrès.
8 communications orales sélectionnées seront présentées à la communauté internationale par les chercheurs et cliniciens de l’Institut :
- Mardi 23 avril
S3L3 • PARALLEL SESSION 1 // MUSCLE FIBROSIS / AGEING
• 11:30 – Capucine Trollet – Cellular actors and ECM components of human fibrosis in myopathies
S4L3 • PARALLEL SESSION 2 // CONGENITAL MYOPATHIES
• 11:30 – Ana Ferreiro – ASC-1 related myopathy reveals transcriptional co-activation as a new regulator of myogenesis: expanding the molecular spectrum and identifying the mechanisms of an emerging congenital myopathy
S5L2 • YOUNG INVESTIGATORS SYMPOSIUM
• 14:30 – Fiorella Grandi – RNA-sequencing of Type II SMA paravertebral muscle after treatment reveals distinct molecular subtypes
- Mercredi 24 avril
S10L2 • PARALLEL SESSION 1 //CMT & NEUROPATHIES
• 10:30 > 12:00 – Tanya Stojkovic – Charcot-Marie-Tooth disease: an overview of genetic and phenotypic variability
S13L1 & L3 • PARALLEL SESSION 1 // OUTCOME MEASURES / PHYSIOTHERAPIES
• 16:00 – Jean-Yves Hogrel – Natural history studies : challenges and limitations
• 17:15 – Harmen Reyngoudt – Longitudinal quantitative MRI of forearm and arm muscles in dysferlinopathy
- Jeudi 25 avril
S17L1 • PARALLEL SESSION 2 // INFLAMMATORY MYOPATHIES
• 10:30 – Olivier Benveniste – Myositis classification for targeted treatments
S18L3 • PARALLEL SESSION 1 // NEUROMUSCULAR JUNCTION
• 15:30 – Rozen Le Panse – Origin of the thymic interferon type I signature in myasthenia Gravis: role of endogenous nucleic acids
3 sessions seront présidées par des experts de l’institut :
- Mardi 23 avril
S2 • PLENARY SESSION // MYOGENESIS
• 08:30 > 10:00 – Fabrice Chrétien
S3 • PARALLEL SESSION 1 // MUSCLE FIBROSIS / AGEING
• 10:30 > 12:00 – Gillian Butler-Browne
- Mercredi 24 avril
S12 • PLENARY SESSION // POSTER FLASH SESSION
• 14:30 > 16:00 – France Pietri-Rouxel
Session poster flash
- Mercredi 24 avril
• 16:00 – présentation orale du poster de Christel Gentil – GDF5 over expression improves physiopathologie of DMD in mdx mouse muscle
Certains experts de l’Institut interviendront lors de trois symposia organisés par des industriels pharmaceutiques :
- Mardi 23 avril
SYMPO2 • INDUSTRY SYMPOSIUM // LUPIN – Myotonia: should we reach a consensus on patient needs?
• 13:30 – Guillaume Bassez – Debate – expert opinions on myotonia in myotonic dystrophies (DM) and non-dystrophic myotonia (NDM)
- Mercredi 24 avril
SYMPO6 • INDUSTRY SYMPOSIUM // ALEXION – Legacy and Innovation: The Potential of Complement in Myasthenia Gravis
• 17:30 – Anthony Béhin – Burden of Disease and Role of Complement in MG
• 18:30 – Anthony Béhin – MG Treatment guidelines in the context of Clinical Practice in France
En parallèle, 46 posters scientifiques seront présentés et expliqués par les chercheurs de l’Institut de Myologie tout au long du congrès, lors des sessions posters, dans le hall Havane :
Valérie Allamand – Refined pro-fibrotic cellular models for detailed extracellular matrix analysis in collagen VI-related dystrophies
Manon Beaujean – Myopilot, a project to compare the regenerative efficacy of several categories of myogenic progenitors in vivo
Louise Benarroch – Cellular and genomic features of myo-converted fibroblasts, an alternative cellular model to myoblasts
Marion Benoist – Machanosensitive clathrin and dynamin 2 platforms regulate YAP/TAZ signaling in skeletal muscle and rare defective in centronuclear myopathy
Anne Bertrand – In vivo gene therapy for striated muscle laminopathy
Rabah Ben Yaou – DYS: the French registry dedicated to Dystrophinopathies
Anne Bigot – Human myoblasts and FAPs cell lines: easy-to-use models to study neuromuscular diseases
Simone Birnbaum – Exercise training for autoimmune myasthenia gravis (MG): A review of safety and effectiveness based on existing literature
Simone Birnbaum – A French version of the modified Spinal Muscular Atrophy Functional Rating Scale (SMAFRS)
Simone Birnbaum – Perceived barriers & facilitators to exercise in autoimmune myasthenia gravis (MG): The MYaEX study
Dounia Bouragba – Human muscle cells secretome in Dysferlinopathy
Aly Bourguiba – Unraveling the role of GDF5 therapeutic potential in Amyotrophic Lateral Sclerosis
Ericky Caldas de Almeida Araujo – Changes in water compartmentation in the skeletal muscle of Golden Retriever Muscular Dystrophy (GRMD) dogs revealed by T2 relaxometry and intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI)
Linda Chenane – Deciphering the link between interferon stimulated genes and regeneration using spatial transcriptomics in dermatomyositis
Catherine Coirault – A-type lamins are crucial to preserve chromatin states during mechanical loading in skeletal muscle
Valérie Decostre – Quantification of skeletal muscle weakness in adult patients with laminopathies
Céline Douarre – Role of the microtubule-associated protein Stathmin 2 in the post-synaptic differentiation of the neuromuscular junction
Nadine Dragin – IL-23/Il-17 involvement in thymic and neuromuscular defects in autoimmune myasthenia gravis
Sestina Falcone – CaVβ1A and CaVβ1E embryonic isoforms in adult skeletal muscle, a Mbnl1 related-expression
Romain Feigean – Key determinants of impaired gait in adults with neuromuscular disease : a multiparametric and multimodal analysis
Anne Forand – Long-term dystrophin replacement therapy causes cardiac inflammation in a severely affected mouse model for Duchenne Muscular Dystrophy
Yves Fromes – MR-based characterization of muscle aging in a cohort of healthy volunteers
Yves Fromes – Effect of low potassium diet and GDF15 on muscle tissue
Maxime Gelin – Exploring the role of GDF5 in neuromuscular system during growth and physical activity
Stéphanie Godard-Bauché – Role of lamin A/C in the maintenance of AChR at the neuromuscular junction in Emery-Dreifuss muscular dystrophy.
Grégoire Haouy – Deciphering the role of R-loops in CTG repeat instability involved in DM1
Edouard Hemery – Characterization of human thymic macrophages in Myasthenia Gravis
Abdessamad Kachal – Predictive Model to Identify Higher Risk of Non-Invasive Ventilation in DM1 Patients
Marie Kervella – Three-dimensional Genome Architecture in Cardiac Muscle Cells: Pathophysiological Implications in Dilated Cardiomyopathy Caused by LMNA gene mutations
Marine Leconte – DNA damage repair in LMNA-related congenital muscular dystrophy
Célia Martin – MBNL deficiency in spinal motor neurons compromises neuromuscular junction maintenance and gait coordination: implication for Myotonic Dystrophy
Benjamin Marty – Quantitative magnetic resonance imaging for predicting disease progression in thigh muscles of Duchenne muscular dystrophy patients
Béatrice Matot – Development of a pipeline to compare magnetic resonance imaging with histological analysis of mouse skeletal muscles
Sabrina Mazzucchi – Investigating the role of SMN1 in R-loop formation during Spinal Muscular Atrophy (SMA) pathogenesis
Pauline Megalli – Implication of mutant DMPK RNA expressed in motor neurons in Myotonic Dystrophy type 1
Hadidja Rose Mouigni – Study of potential regulators of PABPN1 in skeletal muscle
Laura Muraine – Cellular actors and ECM components of human fibrosis in myopathies
Isabelle Nelson – Clinical, morphological and proteomic features of patients suspected of X-linked myopathy with excessive autophagy (XMEA)
Sofia Sosa-Marmol – Improving the immunomodulatory capacities of mesenchymal stem cells and their extracellular vesicles in view of treating Myasthenia gravis
Alain Sureau – Development of an inducible mouse model for Myotonic Dystrophy
Stéphanie Tomé – Single-Molecule long read sequencing in Myotonic Dystrophy type 1
Massiré Traoré – GDF5 as rejuvenating treatment for age-related neuromuscular failure
Delphine Trochet – Development of versatile allele-specific siRNAs able to silence all DNM2 mutations
Frédérique Truffault – Juvenile Myasthenia Gravis in a French cohort: Focus on thymic histology
Stéphane Vasseur – Biological ressources center for research
Laura Virtanen – Single-cell Spatio-Temporal profiling of striated muscle cell populations in Duchenne Muscular Dystrophy
