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RESEARCH
Center of Research in Myology
The Center of Research in Myology brings together nine scientific teams whose shared scientific priorities are basic research, research into neuromuscular diseases and therapeutic applications
Center of Research in Myology
Created on 1 January 2014, the Center of Research in Myology is headed by Denis Furling, PhD, assisted by Marc Bitoun, PhD. It is a centre of research excellence dedicated to understanding the basic mechanisms of muscle within its environment (cellular, such as neurons and inflammatory cells, or at whole-body level, including other organs targeted by muscle diseases such as the heart) and to translating these discoveries into new concepts to improve care for patients with muscle diseases.
The Center of Research in Myology is a Joint Research Unit in Health (UMRS 974) with two supervisory bodies: Sorbonne University and the French National Institute of Health and Medical Research (Inserm). It also benefits from a privileged partnership with the Institute of Myology Association (AIM, “Association Institut de Myologie” in French).
This multidisciplinary research centre comprises nine teams and brings together around 150 researchers, physicians, engineers, technicians, postdoctoral researchers and PhD students from Inserm, Sorbonne University, the French National Centre for Scientific Research (CNRS) and AIM, working on basic research, research into neuromuscular diseases and therapeutic applications covering muscle, the neuromuscular junction and the motor neuron.
Team 1: Gisèle Bonne, PhD and Valérie Allamand, PhD
Genetics and pathophysiology of neuromuscular diseases linked to the extracellular matrix and the nucleus
Team 2: Marc Bitoun, PhD and Stéphane Vassilopoulos, PhD
Muscle cell organisation and therapy for dominant centronuclear myopathy
Team 3: Capucine Trollet, PhD
Cellular and molecular orchestration in muscle regeneration, during ageing and in disease
Team 4: Denis Furling, PhD and Geneviève Gourdon, PhD
Repeat Expansion & Myotonic Dystrophy (REDs)
Team 5: France Pietri-Rouxel, PhD
Maintenance of muscle mass and function, optimising AAV-based gene therapies (MOOVE)
Team 6: Piera Smeriglio, PhD
Biotherapy for motor neuron diseases (ALS & SMA)
Team 7: Rozen Le Panse, PhD
Myasthenia gravis: aetiology, pathophysiology & therapeutic approach
Team 8: Prof. Olivier Benveniste, MD, PhD and Dr Yves Allenbach, MD, PhD
Inflammatory myopathies & innovative targeted therapies
Team 9: Antoine Muchir, PhD
Signalling pathways & striated muscles
The expertise of the teams at the Center of Research in Myology
The research carried out by the teams at the Institute’s Center of Research in Myology covers muscle and muscle disease, the neuromuscular junction and the motor neuron.
