Job opportunities

Please find below vacancies available at the Institute of Myology.

 

Research Associate and Engineer (M/F) - Institute of Myology, Paris - France - 07/05/2021

A research associate (ingénieur de recherche) and an engineer (ingénieur d’étude) positions are available in the BOND group, at the Myology Center for Research, Sorbonne University, INSERM U974, Institute of Myology (Pitié-Salpêtrière hospital, Paris).

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder characterized by the progressive loss of motor neurons and voluntary muscle function and with no effective cure to date. Our laboratory is specialized in biotherapies for motor neuron disorders and demonstrated the effect of a gene therapy vector and an exon skipping strategy to reduce the production of toxic SOD1 in a murine model of the disease (Biferi et al., Mol Ther, 2017).

We are currently characterizing a novel AAV-based therapy for the most common genetic form of ALS caused by hexanucleotide repeats expansion in the C9orf72 gene. In collaboration with an industrial partner, the following positions will be available to study the therapeutic effects of our treatment in experimental models using lentiviral and adeno-associated viral vectors.

Candidates will be selected according to the following criteria:

Engineer: Master 2 and at least 3-year experience in a research laboratory;

Research Associate: PhD in Biology with 3-year experience in a research laboratory;

Strong experiences in cell biology, molecular biology and gene transfer using lentiviral vectors. Expertise in induced pluripotent stem cell (iPSC) manipulation is required. Background in pathophysiology of nucleotide repeat expansion diseases and genome instability will be an advantage.

To complete the project successfully, we are looking for highly motivated scientists with strong scientific background in biomedical sciences, good ability to work in a collaborative environment, knowledge of English and good communication skills. The candidates should be able to work independently, under the supervision of a researcher.

The Myology Centre for Research offers a unique environment for research and development of innovative therapies for neuromuscular diseases. Candidates will therefore have the opportunity to work in a stimulating and enriching context.

The positions are to be filled immediately and the salaries will be established based on the candidate’s experience.

The duration of the contracts is 24 months.

Candidates can send their CV, cover letter and contact information of two references to the following email addresses:
p.smeriglio@institut-myologie.org and m.cappella@institut-myologie.org

Access the complete announcement Research Associate and Engineer (M/F) 

 


Clinical Research Physician (M/F) - Institute of Myology, Paris - France - 01/04/2021

Located in Paris in the heart of the largest European hospital, the Pitié-Salpêtrière, the Institute of Myology was created in 1996 by AFM-Téléthon, a patient’s organization. Its objective is to promote the recognition and development of myology as a standalone clinical and scientific discipline. The Institute of Myology coordinates, around the patient, medical care, basic research, applied research, clinical research and teaching. The Institute of Myology Association, an association under the law of 1901, was created in 2005 by the AFM-Téléthon as a support structure for this group.

The I-Motion Adults platform, located within the Institute of Myology and created in July 2019, is a clinical research platform dedicated to the implementation and conduct of clinical trials on neuromuscular diseases affecting adult patients. Located in the Pitié-Salpêtrière Hospital, the platform works in close collaboration with the Neuromyology Department, the Hospital’s Reference Center for Rare Neuromuscular Diseases and the I-Motion Pediatric platform at the Trousseau Hospital. There is also constant interaction with the research teams of the Research Center in Myology as well as with the various entities within the AFM-Téléthon galaxy (Généthon…).

The Institute of Myology is recruiting a Clinical Research Physician for the I-Motion Adults platform.

This position is to be filled on a full-time permanent contract and is based at the Institute of Myology (Hôpital Pitié-Salpêtrière, Paris 13)

 

Please send your application (CV + cover letter) by e-mail to the following address: recrutement-aim@institut-myologie.org

 

Access the complete announcement Clinical Research Physician (M/F)


Radiographer (M/F) - Institute of Myology, Paris - France - 15/01/2021

Situé à Paris au cœur du plus grand centre hospitalier européen, la Pitié-Salpêtrière, l’Institut de Myologie est né en 1996 sous l’impulsion d’une association de malades et parents de malades, l’AFM- Téléthon. Son objectif : favoriser l’existence, la reconnaissance et l’essor de la myologie en tant que discipline clinique et scientifique à part entière. L’Institut de Myologie coordonne, autour du malade, la prise en charge médicale, la recherche fondamentale, la recherche appliquée, la recherche clinique et l’enseignement. Demain, la Fondation de Myologie, en cours de création, permettra de pérenniser et d’élargir les actions de l’Institut de Myologie. La Fondation aura comme objectif l’étude du muscle, véritable modèle d’innovation pour la recherche médicale, dans tous ses états qu’il soit malade, sain, accidenté, entrainé ou vieillissant.
L’Association Institut de Myologie, association de statut loi 1901, a été créée en 2005 par l’AFM- Téléthon comme structure support de cet ensemble.

Contexte
Le laboratoire de RMN, situé au sein de l’Institut de Myologie à Paris, a pour mission de produire et d’évaluer des outils de mesure par RMN des pathologies affectant le muscle. Il est constitué d’une équipe fortement pluridisciplinaire (physique de la RMN, médecine, biologie, informatique) dont l’éventail d’activité s’étend du développement de nouvelles méthodologies (contrastes d’imagerie, méthodes d’acquisition, post-traitements, etc.) à la réalisation d’études cliniques pour déterminer l’efficacité d’un traitement ou suivre l’histoire naturelle d’une maladie. Il réalise des IRM dans le cadre de protocole de recherche clinique.

Poste à pourvoir dès que possible en CDI à temps plein.

 

Thank you to send your application (CV + cover letter) by e-mail to the following address: recrutement-aim@institut-myologie.org

Access the complete announcement Radiographer (M/F)  (in French)


Bio-informatic engineer - Projet manager (M/F) - Institute of Myology, Paris - France - 15/01/2021

Located in Paris at the heart of the largest European hospital, Pitié-Salpêtrière, the Institute of Myology was created in 1996 by AFM-Telethon, a patient’s organization. Its goal: Promote Myology and have it accepted as a standalone clinical and scientific discipline. The Institute of Myology coordinates around the patient, medical care, basic research, applied research, clinical research and teaching.

Main Purpose

The Strategic plan of the Institute of Myology has a specific objective focus on digitalization.

A digital task force, recently created, would like to address new unmet needs regarding data management, computerized science, data analytics and bioinformatics project to prepare a future Muscle hub and the Medical Artificial Intelligence projects focused on NeuroMuscular and rare diseases.

The project manager will have to support more than 15 teams (Myology research center, Imaging, evaluation, histopathology, Myobank, clinical trials, healthcare professionals in the service of Neuro-Myology…) that would like to synchronize decades of unharmonized data and write the future with standardization, compliance, interoperability and AI to share their expertise with colleagues, Academics, start-ups and other partners.

There is a possibility of evolution, creating a specific department as a data platform with a team after clarification of the overall project.

Role

This role will require an overarching view on all relevant activities and liaising closely with key stakeholders to ensure the needs and input of the strategic digital task-force as a coordinator a first point of contact and a comprehensive support service for partners, experts and the steering committee.

The project manager includes direct line management and development of the Strategic Director in the Coordination team.

This permanent contract, based at the Institute of Myology (Hôpital Pitié Salpêtrière, Paris 13), is to be filled on a full-time basis.

Thank you to send your application (CV + cover letter) by e-mail to the following address: recrutement-aim@institut-myologie.org

Access the complete announcement Bio-informatic engineer – Projet manager (M/F)


Fellow (M/F) for the service of Neuro-Myology - Institute of Myology, Paris - France - 10/11/2020

The fellow’s activity includes training and practice and encompasses the clinical, electromyographic and pathological aspects of the main neuromuscular disorders. Involvement in the clinical research projects of the center is possible and encouraged.

This fixed term contract, based at the Institute of Myology (Hôpital Pitié Salpêtrière, Paris 13) is to be filled on a full-time basis.

Thank you to send by e-mail your application (CV + motivation letter) to the following address: recrutement-aim@institut-myologie.org