Bruno Cadot is head of research in the ‘Signalling pathways and striated muscles’ team led by Antoine Muchir at the Center of Research in Myology . His work has led him to make extensive use of imaging to study muscle and to collaborate with the Institute’s Morphological unit*, which produces and studies sections of patient muscle.
Bruno Cadot therefore proposed combining their two areas of expertise to offer the scientific, educational, medical and research communities the first image database on muscle: the Muscle Atlas. Continuously enriched, it currently includes around 6,500 images, and the aim is to continue to add to it regularly to reach at least 20,000 images by 2028.
Since the diagnosis of neuromuscular diseases is largely based on analyses carried out by the histopathology laboratory, this ground-breaking Atlas is a valuable diagnostic aid. By way of example, the latest tests carried out to identify congenital diseases have shown a success rate of over 90%. This could make medical diagnoses easier and quicker, and prevent patients waiting to be diagnosed from having to wait years for a diagnosis of this type of rare disease.
Using the large number of images available in the histopathology laboratory for numerous neuromuscular diseases, the Institute’s research and clinical teams have created an AI tool that is unique in the world and will speed up diagnosis for the benefit of all patients.
Watch Bruno Cadot’s interview
*Currently led by Teresinha Evangelista, this team has been analysing muscle sections from the tissues of 20,000 patients since the 1980s, providing a remarkable and invaluable pool of knowledge.
