Publication of a review of the literature concerning neuromuscular complications in connection with vaccination against COVID-19

An Iranian team has carried out an exhaustive review of the literature to determine the extent and nature of neuromuscular complications linked, directly or indirectly, with the COVID-19 pandemic:

  • from an initial extraction of 879 publications in several databases, 133 articles caught her attention,
  • they corresponded to 258 individuals, including 171 cases of Guillain-Barré syndrome, 40 of Parsonage-Turner syndrome, 22 of autoimmune myasthenia, 19 of facial paralysis, 5 of small-fiber neuropathy and 1 of Tolosa-Hunt syndrome,
  • in two-thirds of cases, these complications occurred within two weeks of vaccination,
  • the type of vaccination does not seem to be a factor, and the people concerned were mainly adults.

These studies only partially reflect the real-life situation, as many of these complications are not or no longer reported or published.

 

Neuromuscular diseases associated with COVID-19 vaccines: a systematic review and pooled analysis of 258 patients. Tayebi A, Samimisedeh P, Jafari Afshar E et al. BMC Neurol. 2023 Dec.