This is the finding of a one-year Korean study which compared 4,092 patients on statins + metformin with 8,161 patients on statins alone.
Analysis of data from the Korean national health insurance system revealed an incidence of statin-related muscular symptoms of 201.7 per 1000 people on statins alone and 184.3 per 1000 on statins and metformin, irrespective of the statin used.
A larger study would enable us to better identify the longer-term effects of statin-metformin co-medication.