US recommendations on the use of immunoglobulins in MNM

Immunoglobulins are still widely prescribed for certain neuromuscular diseases of autoimmune origin, despite the absence of irrefutable scientific evidence. The scarcity of this type of pharmaceutical product has prompted American doctors to reflect on their proper use in neuromuscular diseases:

  • the initial consensus drawn up in 2009 by the American Association of Myology (AANEM) was reviewed by a panel of experts;
  • this revision included major events in the field, such as the results of clinical trials and/or the approval of certain products by the health authorities;
  • all neuromuscular dysimmunity diseases are reviewed.

Immunoglobulins have no place in the long-term treatment of myasthenia gravis or inclusion myositis.

 

Updated consensus statement : Intravenous immunoglobulin in the treatment of neuromuscular disorders report of the AANEM ad hoc committee. Tavee J, Brannagan TH 3rd, Lenihan MW. et al. Muscle Nerve. 2023 Jul 11.