Italian researchers studied 117 patients with mitochondrial pathologies with muscle expression.
- Three groups were formed (purely muscular mitochondriopathy, progressive external ophthalmoplegia [PEO] and mixed)
- The follow-up was spread over 20 months and included the performance of numerous functional tests (six-minute walk test, Time Up & Go, sitting position test, timed swallowing test, chewing test, etc.)
- An evaluation of fatigue and pain phenomena completed the study.
It was thus possible to determine evolutionary profiles specific to each subgroup for future therapeutic trials.
