A retrospective analysis of 64 lung transplants performed by 19 expert centers in Europe (including France) in adults with myositis complicated by interstitial lung disease shows:
- a survival rate of 78% at one year after transplantation, 73% at 3 years and 70% at 5 years, i.e. figures similar to those of transplant recipients with another pathology;
- a poorer prognosis in case of muscular expression of myositis than in its absence (amyopathic form);
- a rate of severe complications (acute rejection, chronic graft dysfunction) also comparable to the data available for lung transplants in other indications;
- a post-transplant relapse of myositis in muscle or skin in only 8% of cases;
- no recurrence of interstitial lung disease after transplantation.
These results support the idea that myositis in itself is not a contraindication to lung transplantation.
