Mechanisms and future treatments for myasthenia gravis debated at International Society of Neuroimmunology (ISNI) congress

Supported by AFM-Telethon, the 15th edition of the International Society of Neuro-immunology congress was held online from November 8 to 12, 2021. It was co-chaired by Prof. Sonia Berrih-Aknin, from the Institute of Myology. During a session dedicated to myasthenia gravis, in its communication, the Rozen Le Panse team: 

  • reminded that this complex disease of the neuromuscular junction is multifactorial, combining genetic predispositions and epigenetic modulation, plural immune dysfunctions and environmental factors (drugs, endocrine disruptors, stress, etc.); 
  • reported encouraging preclinical results from two therapeutic approaches in development: one concerning a cell therapy with immunomodulatory purposes and the other using an antibody to inhibit the effects of interleukin-23.