Chronic Inflammatory Demyelinating Polyneuropathy

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an acquired demyelinating polyneuropathy sometimes confused with another demyelinating neuropathy, Charcot-Marie-Tooth disease type 1 (hereditary).

 

Clinical trials conducted at the Institute :

  • ARGX-113-1802 – ADHERE: A Phase 2a/2b, Randomized, Double-Blinded, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of Efgartigimod PH20 SC in Patients With Active Idiopathic Inflammatory Myopathy (IIM)
  • ARGX-113-1902 – ADHERE +: Open-label Extension of the ARGX-113-1802 Trial to Investigate the Long-term Safety, Tolerability, and Efficacy of Efgartigimod PH20 SC in Patients With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
  • EFC17236-Sanofi Mobilize: A Phase 3, double-blind, placebo-controlled study evaluating efficacy and safety of riliprubart in participants with refractory chronic inflammatory demyelinating polyneuropathy
  • pHeNIx : Hizentra® in inflammatory neuropathy. pHeNIx study
  • ARISE-JANSSEN : Phase 2/3, Multistage, Multicenter, Randomized, Double-Blind, Placebo-Controlled Parallel Group Withdrawal Study to Evaluate the Efficacy and Safety of Nipocalimab Administered to Adults with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

 

Acronym

ARGX-113-1802 – ADHERE

ARGX-113-1902 – ADHERE +

EFC17236-Sanofi Mobilize
Intervention efgartigimod efgartigimod Riliprubart
Principal investigateur  R. Debs R. Debs K. Viala
Sponsor Argenx Argenx SANOFI
Study status Active Active Active
Recruitment status Completed Completed Ongoing
Population Adult Adult Adult
+ infos on clinicaltrials.gov + infos on clinicaltrials.gov + infos on clinical trials.gov

 

Acronym

pHeNIx

ARISE-JANSSEN
Intervention Hizentra nipocalimab
Principal investigateur  C. Benoist K. Viala
Sponsor CSL Behring JANSSEN
Study status Active In preparation
Recruitment status Ongoing Not started
Population Adult Adult
  + infos on clinicaltrials.gov + infos on clinicaltrials.gov

 

Contact : essais-adultes@institut-myologie.org