Our science & medical news
RSS feedA strategy to effectively prevent sudden cardiac death in DM1
In order to prevent sudden cardiac death in patients with DM1, cardiologists recommend the implantation of a pacemaker in asymptomatic patients with specific abnormalities detectable by electrocardiogram (ECG) or electrophysiological study (EPS). In order to determine which strategy, based on ECG or EPS, is most effective in predicting major bradyarrhythmic events (MBAE) in patients, French … [Read more]
Researchers from the institute attending the MYO-MRI+ conference
The 5th International Imaging in Neuromuscular Disease Conference organised by the MYO-MRI+ consortium will be held in Berlin, Germany, from 9 to 11 November 2025. This conference aims to promote exchanges between radiologists, neurologists, biologists, physicists, engineers and other scientists involved in neuromuscular imaging, with a particular but not exclusive focus on MRI and spectroscopy. … [Read more]
Case report of DNAJB4-related myopathy in France
Myologists from the Paris region, including an expert from the Institute, report the case of a patient with an ultra-rare myopathy: the clinical picture combined a predominantly distal motor deficit in the upper limbs with acute respiratory failure. In addition to CPK levels more than ten times higher than normal, the forced vital capacity at … [Read more]
Three case reports suggest the efficacy of eculizumab in dermatomyositis and myasthenic crisis
Already indicated for refractory forms of myasthenia gravis, eculizumab (Soliris®) has been shown to be effective in two other indications: French clinicians, including experts from the Institute, achieved complete and rapid remission in two patients with dermatomyositis when eculizumab was administered in addition to immunosuppressive therapies. The two young women did not relapse after four … [Read more]
Immunomodulatory mesenchymal cells useful in myasthenia gravis
A group of researchers coordinated by the Institute of Myology has focused on a small contingent of cells and their potential use in the treatment of myasthenia gravis (MG): these stromal cells derive from the mesenchyme and play a role in regulating immunomodulation when they are brought into contact with mononuclear blood cells, several functional … [Read more]
Mitochondrial abnormalities, a possible marker of unfavourable progression in inflammatory myopathies
The presence of mitochondrial abnormalities is now a criterion for the diagnosis of sporadic inclusion myositis. It is also a predictive marker of progression in other forms of inflammatory myopathies, according to a multicentre study involving researchers from the Institute of Myology (Paris): among 850 patients with myositis, 25 had COX-negative fibres (rate of 0.25 … [Read more]
Researchers from the Institute attending the ESGCT conference
The 32nd Annual Meeting of the European Society for Gene & Cell Therapy (ESGCT) will be held in Seville, Spain, from 7 to 10 October 2025. It brings together scientists working in the fields of gene and cell therapy from Europe and beyond, and highlights the latest advances in research and techniques in this field. … [Read more]
Review of current and emerging therapeutic strategies in DMD
Duchenne muscular dystrophy (DMD) is a serious, progressive genetic disorder. It is caused by mutations in the DMD gene that result in the absence of dystrophin, an essential structural protein of the sarcolemma. This weakens the sarcolemmal membrane and makes it highly sensitive to mechanical stress. The heart muscle suffers degenerative alterations similar to those … [Read more]
An innovating method of molecular decoding developed to rejuvenate muscle cells
Andrew Ho, a researcher at the Institute of Myology, is the first co-author of an article that has just been published in the June 2025 issue of Cell Stem Cell*. The study reveals that a single injection of PGE2, a lipid naturally produced by the body in response to muscle injury or exercise, not only improves … [Read more]
Institute experts at the WMS 2025 Congress
The 30th International Congress of the World Muscle Society (WMS) will be held from 7 to 11 October 2025 in Vienna, Austria. The Institute of Myology will be well represented, with numerous scientific and clinical experts in attendance to discuss their clinical and fundamental research. Sabrina Sayah (Psychology and Neuropsychology team) will give an … [Read more]
