Inflammatory myopathies
RSS feedThe value of myostatin measurement in the follow-up of inflammatory myopathies
Measuring the activity of an inflammatory pathology such as inclusion myositis or autoimmune necrotizing myopathy is not easy. Researchers at the Institute of Myology in Paris have investigated the hypothesis that the determination of myostatin, a muscle growth inhibitory factor, may be useful in this context: ELISA assays for myostatin and complementary measurement of the … [Read more]
Positive anti-FHL1 antibodies in certain inflammatory myopathies
Australian and Swedish researchers have studied the immunological profile of patients with normal inflammatory myopathies (274) or scleroderma (174) and compared them with those of 100 control participants. The presence of autoantibodies directed against FHL1, a protein with four and a half LIM domains, already implicated in an X-linked hereditary myopathy, was more specifically sought. … [Read more]
Idiopathic inflammatory myopathies: links between interstitial lung disease and myositis-specific autoantibodies
One of the most common extramuscular manifestations of idiopathic inflammatory myopathies is interstitial lung disease. In addition, the diagnosis of IMI includes the search for myositis-specific autoantibodies. In this study, a team of French researchers and clinicians involving experts from the institute, included 257 patients with idiopathic inflammatory myopathies followed between 2003 and 2019. After … [Read more]
