Muscular channelopathies

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An ENMC workshop on anesthesia in NMD

No less than 28 researchers or clinicians (including three French) and two patient representatives from 15 countries participated in the 259th workshop of the European Neuromuscular Center (ENMC). They exchanged between December 2020 and May 2021 around three themes: anesthetic management in various neuromuscular diseases (myasthenia gravis, congenital muscular dystrophies, channelopathies, etc.), with a review … [Read more]

Post hoc analysis and case report support dichlorphenamide in muscle channelopathies

  Dichlorphenamide (Keveyis®) is prescribed to prevent attacks of periodic hypokalaemic and hyperkalaemic paralysis, two muscular channelopathies. A post-hoc analysis of the results of the randomized double-blind placebo-controlled HYP-HOP trial and its open-label extension:  confirms the efficacy of dichlorphenamide at a dose of 100 mg / day in these two indications, with a lasting reduction … [Read more]