An international consortium of clinicians coordinated by the Barcelona Neuromuscular Center has published the results of the analysis of nuclear magnetic resonance (MRI) images acquired in patients with VCP myopathy, a myopathy characterized by inclusion bodies and, inconstantly, Paget’s disease and/or fronto-temporal dementia :
- the images of 80 patients from the large international cohort of 255 patients with VCP myopathy were usable,
- they were analyzed and compared with MRI images of other neuromuscular diseases and with those of control subjects,
- a relatively specific pattern emerged from this analysis, with predominant involvement of the periscapular, paraspinal, gluteal and quadricipital muscles, with a positive STIR sequence in 67% of cases.
