A simple algorithm for predicting respiratory impairment in myotonic dystrophies

German researchers have developed a method to better detect ventilatory disorders in patients with DM1 or DM2 myotonic dystrophy. The method is based on a checklist known as “Respicheck”, which takes into account several clinical parameters coupled with functional respiratory tests:

  • 172 people took part in a complementary study to validate Respicheck,
  • 74 had DM1, 72 had DM2 and 26 were healthy volunteers,
  • respicheck has a list of 27 items and is able to detect patients requiring respiratory equipment,
  • it performed better in patients with DM1 than in those with DM2.

 

Prediction of respiratory impairment in myotonic dystrophies using the ‘Respiratory involvement symptom checklist’ (Respicheck). Gutschmidt K, Wirner-Piotrowski C, Angarita NG et al. Neuromuscul Disord. 2023 May.