Results of a survey on pregnancy in CMT disease

British team conducted a survey of 92 women with Charcot-Marie-Tooth (CMT) disease to assess their experiences of pregnancy and childbirth (171 in total):

  • the participants completed questionnaires on the development of symptoms during pregnancy and potential obstetric complications encountered.
  • The survey was carried out in a single London hospital, on pregnancies that took place between 1980 and 2020.
  • 37% of participants reported an increase in symptoms of the disease (walking, balance, tiredness, etc.) during pregnancy, especially from the 2nd trimester onwards, and transient symptoms in 49% of them.
  • Obstetric complications were no more frequent than in the general population.
  • Epidural anaesthesia was used more frequently, but without any specific complications.

 

Pregnancy and delivery in patients with Charcot-Marie-Tooth disease and related disorders. M. Skorupinska , G. Ramdharry, B. Byrne et al. Obstet Med. 2023 Jun;16(2):83-87