Inclusion body myositis (IBM) is an autoimmune myopathy characterised mainly by damage to the flexor digitorum and quadriceps muscles occurring after the age of fifty. English clinicians point out the existence of two unusual clinical phenotypes.
- In the first, the onset was surprisingly early, around the age of 30 (in one man and one woman)
- In the second, facial muscle involvement, bulbar disorders, macroglossia and breathing difficulties were prominent. In this case, three middle-aged women were involved.
- All patients fulfilled the other clinical and radiological criteria for genuine IMB.
