Low-carbohydrate ketogenic diet and McArdle’s disease: results of an international survey

An international survey of 183 people with McArdle’s disease in 18 countries, including France, was conducted to gather their experiences with the low-carbohydrate, high-fat ketogenic diet. The results show that:

  • one third of the participants have tried this diet,
  • among them, nearly 90% reported positive effects on McArdle’s disease symptoms (exercise intolerance, muscle pain and fatigue)
  • adverse events were rare and generally considered mild to moderate.

These results suggest that the ketogenic diet may be a promising nutritional strategy for patients with McArdle’s disease, but randomized, placebo-controlled clinical trials are needed to confirm its effectiveness.

 

Patient-Reported Experiences with a Low-Carbohydrate Ketogenic Diet: An International Survey in Patients with McArdle Disease Løkken N, Voermans NC, Andersen LK et al. Nutrients. 2023 Feb 7;15(4):843.