The evolution of muscle fibre morphometry during growth is poorly understood. French researchers and engineers involving scientists from the Institute of Myology have used a new image analysis algorithm (Carpaccio.Cloud) to better measure the evolution of several quantitative parameters over time:
- 482 images, corresponding to 83 biopsied deltoid muscles and representing a total of 33,094 muscle fibres, were analysed.
- Gender and pubertal period significantly influence the parameters of size and distribution of fibres between the different types.
Researchers and clinicians now have age-appropriate standards for interpreting muscle biopsies, whether for diagnosis or therapeutic trials.