Quantifying the number and size of muscle fibres remains a complex, repetitive and time-consuming task. It is hampered, in particular, by the low resolution of biopsy images. French engineers and biologists have developed a new artificial intelligence (AI) tool to try to remedy this.
- MyoSOTHES is a tool derived from the fusion of two algorithms that have appeared on the market, Cellpose and QuPath.
- It is configured to analyse images with haematoxylin-eosin (HE) staining.
- The gain over conventional methods of quantification on slices is 31%.
The authors were also able to test it in the context of preclinical therapeutic protocols (sarcoglycanopathy).
