A small-scale study involving 31 adults with FSH and 30 without showed, with regard to extra-muscular manifestations:
- the incidence of gastrointestinal cancer (gastric or colorectal) would be higher in FSH, from the age of 40 years, and not dependent on the length of the D4Z4 repeats,
- an absence of significant difference for other, non-gastrointestinal cancers (without these being mentioned),
- a higher incidence of cardiovascular events, diabetes and hyperlipidaemia in adults with FSH1.
Given the small number of participants, which may cause statistical bias, further large-scale studies will be needed to confirm or not these results.
