Antisynthetase syndrome is part of the inflammatory myopathies (or myositis) known as “overlapping”. Chinese clinicians retrospectively studied a cohort of 113 adults with this form of myositis but free from any neoplastic process and rheumatic disease.
- 25 of them had flare-ups or inflammation more frequently, on average 1.12 times per year;
- this subgroup was at higher risk of developing rapidly progressive Interstitial Lung Disease (ILD);
- patients with anti-PL7 antibodies were over-represented.