Specific anthropometric curves for patients with SMA ?

 

Many children with spinal muscular atrophy (SMA) experience growth difficulties and weight problems as they progress. Italian researchers studied anthropometric data (height and weight) of 133 children with type I SMA and 82 with type II SMA, none receiving innovative therapies.

They compared them to the standard curves established by the WHO. It appears that children with ADS have: 

  • a weight slightly below the standard, 
  • a size slightly below the standards too, but in a more variable way, 
  • a lowered mean body mass index regardless of the age or type of SMA considered.

These data can be used both for monitoring patients and for therapeutic trials. 

 

Growth patterns in children with spinal muscular atrophy. De Amicis R, Baranello G, Foppiani A et al. Orphanet J Rare Dis. 2021 (Sept). 16(1):375.