A retrospective study from Nantes University Hospital characterizes severe cardiac involvement in women transmitting DMD

A team from Nantes University Hospital is launching a retrospective study, led by Prof. Sandra Mercier, geneticist, to describe the forms of severe heart failure in women with dystrophinopathy. Less than 10% of these women suffer from more or less severe heart disease. 

The study will allow a more detailed description of the cardiac involvement, investigation of possible risk factors and specify prevention and follow-up measures. 

It is based on a collection of clinical information from patients with Duchenne muscular dystrophy with severe cardiac involvement (left ventricular ejection fraction ≤ 35%) from the doctors who follow them, by the team in charge of the study.

Contacts : Sandra.MERCIER@chu-nantes.fr ; solene.conrad@chu-nantes.fr