Electrical impedance myography (EIM) is a non-invasive electrophysiological technique that characterises muscle properties through bioimpedance. This study compared EIM measurements to function, strength, and disease severity in 41 patients with congenital muscular dystrophy (CMD). They had either collagen 6 related disorders (COL6-RD) (n = 21) or laminin alpha 2-related disorders (LAMA2-RD) (n = 20) and 21 healthy paediatric controls underwent 2 yearly EIM exams. In the CMD cohorts, EIM was compared to functional and strength measurements. Both CMD cohorts exhibited change over time and had correlation with disease severity. The 50 kHz phase correlated well with function and strength in the COL6-RD cohort but not in the LAMA2-RD cohort.