Ten-year clinical experience with corticotherapy for DMD patients

annals-of-phys-rehab-med-sep16In France, corticosteroid therapy has been widely used for DMD since 2005 and has changed the practice of pediatric rehabilitation teams. Here, the authors describe their 10-year clinical experience of treating DMD patients with corticosteroids (CS) according to international guidelines i.e. prednisone 0.75mg/kg/day started from the plateau of motor function. Increased appetite, irritability, cushingoid facies are common but well tolerated by children. Dose adjustments are discussed on a case by case basis depending on accelerated weight gain, sluggish growth in stature and behavioral disorders.

Fontaine Carbonnel S, Rippert P, Poirot I, Gachet D, de Lattre C, Vuillerot C. 2005-2015: Ten years clinical experience in treating DMD patients by corticosteroids in Lyon. Ann Phys Rehabil Med. 2016 Sep;59S:e82.