Blog Archives
Results of a European survey on the management of bone problems in neuromuscular diseases
The partial or total immobility caused by many neuromuscular diseases, whether or not associated with the deleterious effect of corticosteroid therapy, is often the cause of bone problems (osteoporosis, osteopenia, fractures, compression, etc.): The Euro-NMD neuromuscular reference network (ERN) has conducted a double survey on these complications, which are frequently encountered over the long term, … [Read more]
A new murine model of myasthenia gravis that is more effective and better suited to animal welfare
The Myasthenia gravis, etiology, pathophysiology & therapeutical approaches team, led by Rozen Le Panse at the Institute of Myology’s Myology Research Centre, has developed a new experimental murine model of myasthenia gravis (N-EAMG) that is at least as effective as the classic experimental model (C-EAMG) and offers several advantages. N-EAMG: is better suited to animal … [Read more]
Identification of effective, non-invasive MRI markers in LGMD R9
French researchers from the Institute of Myology, Genethon and Atamyo, in collaboration with Dutch researchers, have studied several quantitative MRI parameters in order to identify sensitive and non-invasive biomarkers for assessing the progression of LGMD-R9 and evaluating the efficacy of new therapies. Carried out in 18 persons with LGMD-R9 and 13 controls, this study shows … [Read more]
The benefit of reusing data from placebo groups in inclusion myositis
American researchers associated with the Institute of Myology Research Centre have compiled and re-analysed the data accumulated in the placebo arms of several clinical trials in inclusion myositis (IMM) : 11 therapeutic trials were selected, they involved 257 participants who had received only a placebo, the main endpoints were changes in muscle strength and, in … [Read more]
On Saturday 7th of June, the Institute of Myology is holding an Open Day
To mark the 3rd edition of the Muscle Week, the Institute is holding an Open Day on Saturday 7th of June, from 10am to 5pm. Visitors will be able to meet our scientific experts, doctors and researchers to discover muscle in all its states, understand how it works and the interactions it weaves throughout our bodies. … [Read more]
The RMN lab offers a PhD opportunity on the development of real-time quantitative MRI for muscles involved in respiration, swallowing and eye movements
PhD opportunity at the Nuclear Magnetic Resonance Laboratory at Institute of Myology. Development of real-time quantitative MRI for muscles involved in respiration, swallowing and eye movements Keywords: Muscle MRI, real-time MRI, undersampled reconstruction, non-Cartesian MRI acquisition ➣ Context Quantitative MRI (qMRI) is a well-established tool for the in vivo characterization and longitudinal monitoring of skeletal … [Read more]
The RMN lab offers a PhD opportunity on Low Field MR-Fingerprinting for respiratory assessment
PhD opportunity at the Nuclear Magnetic Resonance Laboratory at Institute of Myology. Low Field MR-Fingerprinting for respiratory assessment Keywords: Low-field MRI, sequence development, undersampled reconstruction and optimization, AI-based denoising, respiratory function. ➣ Context Pulmonary and muscle tissues involved in the respiratory function can be affected in various diseases (COPD, neuromuscular diseases, CoViD…). Quantitative MRI has … [Read more]
A revision of the classification of congenital myopathies in the light of recent discoveries
The team at the Créteil Neuromuscular Disease Reference Centre takes stock of congenital myopathies in the light of the recent exponential increase in knowledge in this field: in addition to the histological criteria which largely contributed to their original descriptions, genetics has enabled new entities to be discovered and their contours to be better defined, … [Read more]
M&M’s – Muscle Monday Seminar – 12 May – Remi Mounier (France)
Metabolic regulations of adult muscle stem cell fate Monday 12 May 2025 – 12h00-13h00 Remi Mounier (NeuroMyoGène, Lyon, France) More information on the presentation and the speaker On prior registration for people outside the Institute of Myology: medecine-umrs974-myologie@sorbonne-universite.fr M&M’s seminar organised by the Center of Research in Myology, at the Institute of Myology.
Immune-mediated necrotising myopathy in children, a Chinese picture
A study conducted by a hospital in Beijing (China) has refined our knowledge of the phenotype of immune-mediated necrotising myopathy in paediatrics: 55 of the 116 children and adolescents followed up for myositis by this centre between 2012 and 2024 had immune-mediated necrotising myopathy, a much higher proportion (47.4%) than expected, but one that would … [Read more]
