The Danish experience with myasthenia gravis

Danish researchers report the results of a large epidemiological study on mortality observed in myasthenia gravis between 1985 and 2020:

  • the information was drawn from existing health data warehouses in Denmark,
  • mortality figures were defined according to the date of occurrence of the event (within one year [short term], or between 1 and 5 years [medium to long term]), and compared, after matching, with those of the general population,
  • the cohort of patients with myasthenia gravis comprised a total of 2,110 people,
  • short-term mortality was significantly higher than that observed in the general population, especially among people over the age of 75.
  • However, long-term mortality was similar to that of the general population

The authors emphasize the need for early diagnosis and proactive treatment in this age group, especially in the first year.

 

Mortality in Myasthenia Gravis in Denmark From 1985 to 2020: A Population-Based Cohort Study. Jul Jarbæk Nielsen J, Levison L, Andersen H. Neurology. 2025 Jun