The CATSS-O retrospective study, for Calcifications Treated by Sodium Thiosulphate – Observational, included data acquired between 2014 and 2020 from 35 patients, including 28 with dermatomyositis or scleromyositis with ectopic calcifications that were often multiple (calcinosis).
After six months of daily applications of a sodium thiosulphate-based ointment (25%) prepared by the Limoges University Hospital pharmacy, the volume of calcifications decreased:
- objective regression (X-ray or CT scan) in 32.1% of cases, including total disappearance in three patients,
- stable in 51% of patients
- an increase in volume in the other cases.
The product was well tolerated. Its efficacy appears to be better in children than in adults, although the small number of participants makes it difficult to draw any definitive conclusions.
