To date, a quality of life (QOL) measure specific for MG does not exist in French. Here, translation and cross-cultural adaption of the French Myasthenia Gravis Quality of Life Scale (MG-QOL 15) followed by reliability and validity evaluations were performed in 125 French myasthenic patients. Internal consistency was excellent (Cronbach alpha = 0.92) as was test-retest reliability (ICC = 0.92, 95% CI: 0.86-0.96). Concurrent validity was good for both clinical scores (MMS: rho = -0.52, P <0.001), (MG-ADL score: rho = 0.62, P <0.001). Correlations were strongest for overall QOL (rho = 0.62, P <0.001) and physical health (r = 0.67, P <0.001) on the World Health Organization-Quality of Life short score (WHO-QOL BREF). The MGQOL-15-F is valid and reliable and is now available for use with French-speaking patients.
