An observational study evaluated factors influencing compliance with the initiation of non-invasive ventilation (NIV) treatment for sleep-disordered breathing in 13 adults with myotonic dystrophy type 1 (MD1) or Steinert disease.
- The six patients who did not adhere to NIV had more severe depressive symptoms, with significantly higher median Beck Depression Inventory (BDI-II) scores (18 versus 6 points for patients who adhered).
- Depression was also associated with nocturnal oxygen desaturation.
The authors advocate for the integration of psychological evaluations and the management of mental health disorders, such as depression, to improve NIV compliance.
