In Belgium, a father and daughter :
- developed autoimmune necrotising myopathy with HMGCR autoantibodies a few years apart, following treatment with statins;
- are both carriers of HLA-DRB1*11:01, a variant already identified as being more frequent in this disease.
The case of this Belgian family strengthens the hypothesis of genetic susceptibility to autoimmune myositis. Investigation of the other members of this family could help identify other genetic predisposing factors and, in so doing, consider a preventive strategy, screening patients at risk before starting them on statins.
