Thiamine, or vitamin B1, is important for nerve cell function. Administered as a dietary supplement, it is thought to have beneficial effects in a number of neurological diseases.
Russian researchers have studied its therapeutic value in Charcot-Marie-Tooth disease.
- A pilot study involving 15 patients with CMT 1A showed an improvement in grip strength thanks to daily intake of a high dose of thiamine (100 mg).
- The mechanism of action of thiamine in CMT remains to be determined, but analyses did not show any thiamine deficiency in these patients.
