A Japanese consortium of clinicians reports the clinical and paraclinical data of a large series of patients diagnosed with anti-MuSK antibody-positive myasthenia gravis:
- 51 patients were included in the study from an initial sample of 1,710 patients with myasthenia gravis (3% of the total),
- two patients double-positive for MuSK protein and acetylcholine receptor were excluded beforehand,
- The predominance of the condition in the female population was highly significant, as was the very low frequency of ocular forms and the importance of bulbar forms, in line with the literature on the subject,
- forms resistant to treatment were particularly frequent, probably due to the lesser use in Japan of more aggressive medications such as rituximab.
