This prospective multicentre study aimed to investigate the psychometric properties of the Duke Health Profile (DHP) and its validity among adult patients from centers in Reims, Dijon and Besancon, suffering from slowly progressive neuromuscular disorders (NMD). A total of 139 patients were included. The acceptability of the DHP was excellent. The disability dimension showed marked ceiling effect. Reliability was acceptable (Cronbach = 0.54 – 0.73, except for the social health dimension (0.40), ICC = 0.55 – 0.83). The anxiety and depression dimensions had discriminant properties in distinguishing patients with different functional status. The authors conclude that the DHP is suitable and valid for patients with neuromuscular disease, with some reservations for the social health and disability dimensions.
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