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ERN EURO-NMD

European Reference Networks (ERNs) are networks involving centers of expertise and health care providers across Europe. They aim to tackle complex or rare diseases and conditions that require highly specialized treatment, as well as a concentration of knowledge and resources. Established in 2017 and co-funded by the European Commission, EURO-NMD is a European reference network for the thematic grouping of rare neuromuscular diseases (NMDs), a broad group of related disorders that represent a major cause of mortality and lifelong disability in children and adults.

The network brings together 84 highly specialized multidisciplinary healthcare providers (HCPs) from 25 European countries, as well as 23 patient organisations. It is structured around five disease groups, four cross-cutting diagnostic groups, working groups dedicated to research, ethics and education and a patient advisory board. 

EURO-NMD is currently funded by the European Union’s EU4Health program. The ERN EURO-NMD is a partner in other EU-funded projects, in particular the ERICA consortium, in which all 24 ERNs participate, and the European Joint Programme on Rare Diseases (EJP RD). 

The coordination of EURO-NMD is based in France, at the Institute of Myology located at the heart of the largest European hospital, the Pitié-Salpêtrière, which is part of the Assistance Publique – Hôpitaux de Paris (AP-HP). Currently, the coordination of the ERN is ensured by the AP-HP and operated by a team of 6 people: a coordinator, a clinical advisor, a project responsible, 2 project managers and a communication officer. 

Main objective 

The Project Assistant position will provide day-to-day administrative, organizational and secretarial support to the activities of the Network. 

He/She works under the supervision of the Chief project manager, and in consultation with the ERN team, will connect with the network partners and the European Commission to allow the swift progress of the project. 

Main tasks and responsibilities

The Project Assistant will be involved in a variety of tasks, including but not limited to the following:

• Supporting the non-scientific, administrative, and financial management of the project and project-related activities;
• Conducting administrative tasks, necessary to ensure the smooth running of the project, finances and other activities (time sheets, cost claims, invoices, contracts, etc.);
• Assisting with project related communication & communication between Network members, European Commission, other ERNs and stakeholders;
• Screening incoming daily routine e-mails and forwarding to the adequate person, keeping track of pending matters;
• Setting up internal/external project-related meetings as requested, prepare minutes and follow-up of action points;
• Providing support in organizing travel and other logistics arrangements for online or in-person events and work meetings; which includes but is not limited to drafting and sending invitations and confirming participation of attendees; making travel arrangements, preparing minutes and other materials for distribution;
• Preparing, managing and updating mailing lists;
• Providing support to team members as required;
• Other tasks as appropriate.

Candidate profile

• Fluency in French and English;
• Previous experience with EU-funded projects or equivalent;
• Ability to work in a team, in a multicultural environment.

Skills

• Professional experience relating to administrative and project support duties or similar, ideally in the context of European funded projects;
• Experience in financial monitoring and reporting;
• Excellent knowledge of English and a very good knowledge of French;
• Experience using standard tools in MS Office applications (Word, Excel, PowerPoint, Outlook, etc.);
• Good interpersonal skills;
• Adaptability;
• Highly organised and dynamic.

Desirable

• Experience of undertaking or supporting work in fields relating to health care and research, neuromuscular diseases or rare diseases;
• General knowledge in activities of the European Commission for rare diseases.

Job specifications

• English environment (working language of the network);
• Requires travelling in the EU (occasionally);
• Remote work possible (2 days/week).

Other

• Fixed-term contractual position attached to the Clinical Research and Innovation Delegation (DRCI) of the AP-HP.
• Working hours: 100%.
• Salary according to experience, diploma and APHP’s salary grid.

Please send your application (CV + cover letter) by e-mail to the following address:
c.dangelo@ern-euro-nmd.eu

 

Desired starting date: 01/06/2023

 

Download job description Project Assistant (m/f) in the European Reference Network (ERN) EURO-NMD

A two-year postdoctoral position is available from early 2023, in the laboratory Repeat Expansions and Myotonic Dystrophy, at the Myology Research Centre / Institute of Myology in Paris, France. The project is funded by the French “Agence Nationale de Recherche” (ANR) and coordinated by Mario Gomes-Pereira.

PROJECT SUMMARY | Perturbations of RNA homeostasis are implicated in the aetiology of several pathologies, for which myotonic dystrophy type 1 (DM1) is a paradigmatic example. DM1 is an inherited neuromuscular disease that affects multiple tissues and cell types. The neurological manifestations are exceptionally debilitating, however important gaps still exist in our understanding of brain disease. Based on our recent findings, we believe that DM1 has a major impact on astrocyte morphology, adhesion, and RNA metabolism, with subsequent consequences on brain function. In addition, we propose that MBNL proteins play a role in astrocyte dysfunction. This project will explore the causes and effects of glial dysfunction in DM1, using unique mouse models, patient-derived human induced pluripotent stem cells (hiPSC) and brain organoids. Transcriptomics, bioinformatics and high-resolution imaging will elucidate the mechanisms behind DM1 brain disease, as well as fundamental aspects of RNA biology in astrocytes. More information can be found here.

References: Dincã et al (2022) Nat Commun. doi: 10.1038/s41467-022-31594-9; González-Barriga et al (2021) Front Cell Neurosci. doi: 10.3389/fncel.2021.662035; Sicot et al (2017) Cell Rep. doi: 10.1016/j.celrep.2017.06.006.

LOCATION | The REDS laboratory, headed by D. Furling and G. Gourdon is a leading laboratory in the field of DM1, combining complementary expertise, from genetics and pathophysiology to the development of new therapeutic tools. Our laboratory is located at the Myology Research Centre / Institute of Myology, a renowned institution dedicated to the basic understanding of neuromuscular diseases, and to the translation of fundamental science to the improvement of patient care. The campus of Sorbonne University and Pitie Salpetriere Hospital offer a dynamic environment with state-of-the art facilities and platforms.

QUALIFICATIONS | Candidates must hold a PhD in a relevant subject (molecular biology, cell biology, neuroscience or genetics). They must have received good training in molecular and cell biology. Knowledge of neurobiology is desirable. The successful candidate is expected to be highly motivated, well-organised, have excellent communication skills, a high level of accuracy in all aspects of work and the ability to contribute to a multidisciplinary project and research group with insight and enthusiasm. He/she will (1) provide input into decisions on experimental approaches and techniques; (2) keep up to date with current developments in the field; (3) collaborate with other members of the group and liaise with external collaborators; (4) take a lead in the presentation of results and paper writing. Good knowledge of the English language is essential.

SALARY | Salary will be commensurate with experience following Inserm guidelines.

 

APPLICATION DETAILS | Applications in English should include a cover letter, a detailed CV and the contact details of at least two academic references. Applications and informal inquiries should be e-mailed to Mario Gomes-Pereira (mario.pereira@inserm.fr). Please send your application before the 15^th October 2022.

 

Download the Postdoctoral position complete description