Check the mail online click here
|
|
|
Newsletter #62
|
|
Welcome to the 62nd edition of our newsletter!
This issue brings you, amongst others, news about Myobank, the Biological Resource Center of the Institute of Myology, which evolves in response to the demands of a team from the Myology Research Center.
On 23-24 June, the AFM-Telethon’s Days for Families will take place at the Parc Floral, Paris. About 2500 people are expected to participate in this event where families and patients gather in a festive setting to exchange with experts and obtain information about their neuromuscular disease.
Finally, on June 2nd, the institute will host the 10th day of discussions of the Reference Center for Neuromuscular Pathology in Paris East, on the theme “Inclusion and Citizenship in Neuromuscular Diseases”.
|
At the Institute |
Myobank-AFM broadens its scope
Myobank-AFM has evolved on a regulatory, administrative and logistical level to meet the demand of a team from the Institute’s Myology Research Center.
Read more
|
The AFM-Telethon Days for Families at the Parc Floral, Paris
On 23-24 June, the annual large gathering of the association, its supporters and staff will take place at the Parc Floral, Paris.
Read more
|
Our latest news |
The gene encoding myopalladin involved in cap myopathy
Caps myopathy is genetically heterogeneous with at least three different genes involved. The authors confirm here the implication of the MYPN gene in the genesis of this myopathy.
Read more
|
Gait analysis in GRMD dogs using linear discriminant analysis
The authors describe a new method of 3D accelerometric gait analysis using linear discriminant analysis (LDA).
Read more
|
OPMD: efficacy of dual gene therapy in mice
A team supported by the AFM-Telethon has provided proof-of-concept for the efficacy of a dual gene therapy approach in a mouse model OPMD.
Read more
|
Immortalized human myotonic dystrophy muscle cell lines to investigate molecular pathophysiologic mechanisms
A collaboration with teams from the Institute of Myology has developed a new model of immortalized myotonic dystrophy muscle cells.
Read more
|
Anoctaminopathies: the least severe clinical forms are particularly frequent
Clinicians from the Institute of Myology describe the clinical and paraclinical data of a large cohort of patients in whom recessive mutations of the ANO5 gene have been demonstrated using high-throughput sequencing in a panel of genes.
Read more
|
More breaking news |
SMA: Positive opinion of the EMA for Spinraza™
The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency adopted a positive opinion for Spinraza™ a first step towards market authorisation.
Read more
|
Follistatin gene therapy for sporadic inclusion body myositis improves functional outcomes
Positive results in the first gene therapy trial bringing the follistatin gene into the muscles of patients with sporadic inclusion body myositis.
Read more
|
Duchenne and Becker muscular dystrophies
|
Spinal muscular atrophy
|
Charcot-Marie-Tooth disease
|
Limb-girdle muscular dystrophies
|
Congenital muscular dystrophies
|
Other neuromuscular diseases
|
In brief |
FDA fast track designation for vamorolone: A dissociative steroid for the treatment of DMD
The treatment is being developed as a replacement for existing glucocorticoids, not as an add-on therapy.
Read more
|
Job oppportunity
Post-doctoral positions in skeletal muscle stem cells and molecular medicine are available in the team directed by Pr Frédéric Relaix at Mondor Institute of Biomedical Research (IMRB) in Paris-Est, France.
Read more
|
Latest Publications from the Institute |
Fischer, M.,Rikeit, P.,Knaus, P.,Coirault, C.
YAP-Mediated Mechanotransduction in Skeletal Muscle
Front Physiol, 2016 ; 7 : 41
Galant, D.,Gaborit, B.,Desgrouas, C.,Abdesselam, I.,Bernard, M.,Levy, N.,Merono, F.,Coirault, C.,Roll, P.,Lagarde, A.,Bonello-Palot, N.,Bourgeois, P.,Dutour, A.,Badens, C.
A Heterozygous ZMPSTE24 Mutation Associated with Severe Metabolic Syndrome, Ectopic Fat Accumulation, and Dilated Cardiomyopathy
Cells, 2016 ; 5 (2) : 21
|
|
Newsletter subscription
Every two months, the newsletter from the Institute of Myology informed you on developments in myology research, with a summary of the latest scientifics news, medical, political and community about neuromuscular diseases. You can read our newsletter by subscribing. You can unsubscribe here. |
|
Also follow our news on social networks
|
|
Legal
This is the newsletter of current medical science from the Institute of Myology. It is published every two months. Chief Editor: Marie-Pierre Verrier Editorial Board: Marianne Perreau-Saussine; J. Andoni Urtizberea. Redaction: Racquel N. Cooper; Anne Berthomier. Also participate: Nathalie Haslin; Hala Alameddine; Delphine Alibert. Do you have any questions? Would you like to share some news? Please contact us. © 2017 - AFM - Institut de Myologie. ISSN 1772-9866 |
|