Références de l’équipe
- M.A. Cron, S. Maillard, F. Truffault, A.M. Gualeni, A. Gloghini, E. Fadel, J. Guihaire, A. Behin, S. Berrih-Aknin and R. Le Panse. Cause and consequences of miR-150-5p dysregulation in myasthenia gravis. Frontiers in Immunology (in press).
- S. Berrih-Aknin and R. Le Panse. Thymectomy in myasthenia gravis: when, why, and how? Lancet Neurol. 2019 (Epub ahead of print).
- J.A. Villegas, A.C. Bayer, K. Ider, J. Bismuth, F. Truffault, R. Roussin, N. Santelmo, R. Le Panse, S. Berrih-Aknin and N Dragin. Role of IL-23/Th17 cell pathway: a promising target to alleviate thymic inflammation maintenance in myasthenia gravis. J. Autoimmunity (Epub ahead of print).
- V. Yilmaz, S. Maillard, F. Truffault, F. Bolgert, A. Behin, J.F. Reignard, S. Berrih-Aknin and R. Le Panse. Regulatory B cells in myasthenia gravis are differentially affected by therapies. Annals of Clinical Translational Neurology, 2018.
- J.A. Villegas, A. Gradolatto, F. Truffault, R. Roussin, S. Berrih-Aknin, R. Le Panse and N Dragin. Cultured Human Thymic-Derived Cells Display Medullary Thymic Epithelial Cell Phenotype and Functionality. Frontiers in Immunology 23; 9:1663, 2018.
- M.A. Cron, S. Maillard, F. Delisle, N. Samson, F. Truffault, M. Foti, E. Fadel, J. Guihaire, S. Berrih-Aknin and R. Le Panse. Analysis of microRNA expression in the thymus of Myasthenia Gravis patients opens new research avenues. Autoimmunity Review 17(6): 588-600, 2018.
- M. Robinet, S. Maillard, B. Villeret, M.A. Cron, S. Berrih-Aknin and R. Le Panse. Use of Toll-Like Receptor agonists to induce ectopic lymphoid structures in myasthenia gravis mouse models. Frontiers in Immunology, 25; 8: 1029 2017.
- M. Attia, M. Maurer, M. Robinet, F. Le Grand, E. Fadel, R. Le Panse, G. Buttler-Browne and S. Berrih-Aknin. Muscle satellite cells are functionally impaired in myasthenia gravis: consequences on muscle regeneration. Acta Neuropathologica – 134(6):869-888, 2017.
- N. Dragin, P. Nancy, J. Villegas, R. Roussin and R. Le Panse, and S. Berrih-Aknin. Balance between estrogens and proinflammatory cytokines regulates chemokine production involved in thymic germinal center formation. Scientific reports – 7 (1), 7970, 1-13, 2017.
- N. Dragin, J. Bismuth, G. Cizeron-Clairac, M.G. Biferi, C. Berthault, A. Serraf, R. Nottin, D. Klatzmann, A. Cumano, M. Barkats, R. Le Panse, S. Berrih-Aknin. Estrogen-mediated downregulation of AIRE influences sexual dimorphism in autoimmune diseases. J. Clin. Invest. 126(4):1525-37, 2016.
- J. M. Weiss, M. Robinet, R. Aricha, P. Cufi, B. Villeret, F. Lantner, I. Shachar, M.C. Souroujon, S. Fuchs, S. Berrih-Aknin, R. Le Panse. Novel CXCL13 transgenic mouse: inflammation drives pathogenic effect of CXCL13 in experimental myasthenia gravis. Oncotarget 16-7(7):7550-62, 2016.
- S. Mamrut, N. Avidan, E. Staun-Ram, E. Ginzburg, F. Truffault, S. Berrih-Aknin and A. Miller. Integrative Analysis of Methylome and Transcriptome in Human Blood Identifies Extensive Sex- and Immune Cell-Specific Differentially Methylated Regions. Epigenetics 10 (10), 943-57, 2015.
- P. Cufi, P. Soussan, F. Truffault, R. Fetouchi, E. Fadel, S. Berrih-Aknin and R. Le Panse. Thymoma-associated Myasthenia Gravis: on the search for a pathogen signature. J. Autoimmunity 52: 29-35, 2014.
- P. Cufi, N. Dragin, N. Ruhlman, J. M. Weiss, E. Fadel, A. Serraf, S. Berrih-Aknin and R. Le Panse. Central role of interferon-beta in thymic events leading to myasthenia gravis. J. Autoimmunity 52: 44-52, 2014.
- D. Nazzal, A. Gradolatto, F. Truffault, J. Bismuth and S. Berrih-Aknin. Human Thymus Medullary Epithelial Cells Promote Regulatory T-Cell Generation by Stimulating Interleukin-2 Production Via Icos Ligand. Cell Death Dis. 5, e1420, 1-13, 2014.
- A. Gradolatto, D. Nazzal, F. Truffault, J. Bismuth, E. Fadel, M. Foti and S. Berrih-Aknin. Both Treg Cells and Tconv Cells Are Defective in the Myasthenia Gravis Thymus: Roles of Il-17 and Tnf-Alpha. J. Autoimmunity 52, 53-63, 2014.
- E. Ben-Ami, A. Miller and S. Berrih-Aknin. T Cells from Autoimmune Patients Display Reduced Sensitivity to Immunoregulation by Mesenchymal Stem Cells: Role of Il-2. Autoimmunity Rev 13 (2), 187-96, 2014.
- P. Cufi, N. Dragin, J.M. Weiss, P. Martinez-Martinez, M.H. De Baest, R. Roussin, E. Fadel, S. Berrih-Aknin and R. Le Panse. Implication of dsRNA signaling in the etiology of autoimmune myasthenia gravis. Annals of Neurology 73 (2): 281-93, 2013.
Références en collaboration
- V. Mariot, R. Joubert, C. Hourdé, L. Féasson, M. Hanna, F. Muntoni, T. Maisonobe, L. Servais, R. Le Panse, O. Benvensite, T. Stojkovic, P.M. Machado, T. Voit, A. Buj-Bello, J. Dumonceaux. Reversible endogenous downregulation of myostatin pathway in muscle wasting neuromuscular diseases explains challenges of anti-myostatin therapeutic approaches. Nature communication 30; 8 (1): 1859, 2017.
- C. Stergiou, K. Lazaridis, V. Zouvelou, J. Tzartos, R. Mantegazza, C. Antozzi, F. Andreetta, A. Evoli, F. Deymeer, G. Saruhan-Direskeneli, H. Durmus, T. Brenner, A. Vaknin, S. Berrih-Aknin, A. Behin, T. Sharshar, M. De Baets, M. Losen, P. Martinez-Martinez, K. A. Kleopa, E. Zamba-Papanicolaou, T. Kyriakides, A. Kostera-Pruszczyk, P. Szczudlik, B. Szyluk, D. Lavrnic, I. Basta, S. Peric, C. Tallaksen, A. Maniaol, N. E. Gilhus, C. Casasnovas Pons, J. Pitha, M. Jakubikova, F. Hanisch, J. Bogomolovas, D. Labeit, S. Labeit and S. J. Tzartos. Titin Antibodies in Seronegative Myasthenia Gravis – a New Role for an Old Antigen. J. Neuroimmunology 292, 108-15, 2016.
- A.I. Tsonis, P. Zisimopoulou, K. Lazaridis, J. Tzartos, E. Matsigkou, V. Zouvelou, R. Mantegazza, C. Antozzi, F. Andreetta, A. Evoli, F. Deymeer, G. Saruhan-Direskeneli, H. Durmus, T. Brenner, A. Vaknin, S. Berrih-Aknin, A. Behin, T. Sharshar, M. De Baets, M. Losen, P. Martinez-Martinez, K. A. Kleopa, E. Zamba-Papanicolaou, T. Kyriakides, A. Kostera-Pruszczyk, P. Szczudlik, B. Szyluk, D. Lavrnic, I. Basta, S. Peric, C. Tallaksen, A. Maniaol, C. Casasnovas Pons, J. Pitha, M. Jakubikova, F. Hanisch and S. J. Tzartos. Musk Autoantibodies in Myasthenia Gravis Detected by Cell Based Assay–a Multinational Study. J. Neuroimmunology 284, 10-7, 2015.
- T. Punga, R. Le Panse, M. Andersson, F. Truffault, S. Berrih-Aknin and A. Rostedt Punga. Circulating miRNAs in Myasthenia Gravis: miR-150-5p as a new potential biomarker. Ann. Clin. Trans. Neurol. 1(1): 49–58, 2014.
- N. Avidan, R. Le Panse, H.F. Harbo, P. Bernasconi, K. Poulas, E. Ginzburg, P. Cavalcante, L. Colleoni, F. Baggi, C. Antozzi, F. Truffault, S. Horn-Saban, S. Pöschel, Z. Zagoriti, M. Belimezi, A. Maniaol, B.A. Lie, I. Bernard, A. Saoudi, Z. Illes, C. Casasnovas Pons, A. Melms, S. Tzartos, N. Willcox, A. Kostera-Pruszczyk, C. Tallaksen, R. Mantegazza, S. Berrih-Aknin, A. Miller. VAV1 and BAFF, via NFκB pathway, are genetic risk factors for myasthenia gravis. Ann Clin Transl Neurol. 1(5): 329-39, 2014.
- K. Vrolix, J. Fraussen, M. Losen, J. Stevens, K. Lazaridis, P.C. Molenaar, V. Somers, M.A. Bracho, R. Le Panse, P. Stinissen, S. Berrih-Aknin, J.G. Maessen, L. Van Garsse, W.A. Buurman, S.J. Tzartos, M.H. De Baets and P. Martinez-Martinez. Clonal heterogeneity of thymic B cells from early-onset myasthenia gravis patients with antibodies against the acetylcholine receptor. J. Autoimmunity 52: 101-112, 2014.
- P. Zisimopoulou, P. Evangelakou, J. Tzartos, K. Lazaridis, V. Zouvelou, R. Mantegazza, C. Antozzi, F. Andreetta, A. Evoli, F. Deymeer, G. Saruhan-Direskeneli, H. Durmus, T. Brenner, A. Vaknin, S. Berrih-Aknin, M. Frenkian Cuvelier, T. Stojkovic, M. DeBaets, M. Losen, P. Martinez-Martinez, K. A. Kleopa, E. Zamba-Papanicolaou, T. Kyriakides, A. Kostera-Pruszczyk, P. Szczudlik, B. Szyluk, D. Lavrnic, I. Basta, S. Peric, C. Tallaksen, A. Maniaol and S. J. Tzartos. A Comprehensive Analysis of the Epidemiology and Clinical Characteristics of Anti-Lrp4 in Myasthenia Gravis. J. Autoimmunity 52, 139-45, 2014.
