{"id":2387,"date":"2021-07-20T11:24:00","date_gmt":"2021-07-20T09:24:00","guid":{"rendered":"https:\/\/www.institut-myologie.org\/imotion\/?p=2387"},"modified":"2021-07-23T11:27:11","modified_gmt":"2021-07-23T09:27:11","slug":"dmd-start-at-i-motion-of-trials-with-pamrevlumab-in-ambulatory-and-non-ambulatory-patients","status":"publish","type":"post","link":"https:\/\/www.institut-myologie.org\/imotion\/2021\/07\/20\/dmd-start-at-i-motion-of-trials-with-pamrevlumab-in-ambulatory-and-non-ambulatory-patients\/?lang=en","title":{"rendered":"DMD: start at I-Motion of trials with pamrevlumab in ambulatory and non-ambulatory patients"},"content":{"rendered":"\n<p>I-Motion is recruiting patients with Duchenne muscular dystrophy to participate in two pharmacological trials designed to test an antifibrotic monoclonal antibody, pamrevlumab (or FG-3019), developed by FibroGen.<\/p>\n\n\n\n<p>The objective of these phase III trials is to assess the tolerance, safety and efficacy on the upper limbs, respiratory and cardiac functions of pamrevlumab administered by intravenous infusion in combination with oral corticosteroids in boys. with DMD, over 12 years old, ambulant (trial FGCL-3019-094) or non-ambulant (trial FGCL-3019-093).<\/p>\n\n\n\n<p>Dr Silvana De Lucia is the principal investigator in these two trials at the I-Motion site.<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>Further details on trials&nbsp;<a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT02814019\" target=\"_blank\" rel=\"noreferrer noopener\">FGCL-3019-094<\/a>&nbsp;and <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04371666\" target=\"_blank\" rel=\"noreferrer noopener\">FGCL-3019-093<\/a><\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>I-Motion is recruiting patients with Duchenne muscular dystrophy to participate in two pharmacological trials designed to test an antifibrotic monoclonal antibody, pamrevlumab (or FG-3019), developed by FibroGen. The objective of these phase III trials is to assess the tolerance, safety and efficacy on the upper limbs, respiratory and cardiac functions of pamrevlumab administered by intravenous &hellip; <a href=\"https:\/\/www.institut-myologie.org\/imotion\/2021\/07\/20\/dmd-start-at-i-motion-of-trials-with-pamrevlumab-in-ambulatory-and-non-ambulatory-patients\/?lang=en\">Continued<\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[3],"tags":[],"class_list":["post-2387","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>DMD: start at I-Motion of trials with pamrevlumab in ambulatory and non-ambulatory patients - I-Motion<\/title>\n<meta name=\"description\" content=\"Recruitment of patients with DMD to participate in trials designed to test an antifibrotic monoclonal antibody, pamrevlumab (or FG-3019).\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.institut-myologie.org\/imotion\/2021\/07\/20\/dmd-start-at-i-motion-of-trials-with-pamrevlumab-in-ambulatory-and-non-ambulatory-patients\/?lang=en\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"DMD: start at I-Motion of trials with pamrevlumab in ambulatory and non-ambulatory patients - 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